A machine learning model for predicting the three-year survival status of patients with hypopharyngeal squamous cell carcinoma using multiple parameters

被引:2
|
作者
Li, Z. [1 ,2 ]
Ding, S. [1 ]
Zhong, Q. [1 ]
Fang, J. [1 ]
Huang, J. [1 ]
Huang, Z. [1 ]
Zhang, Y. [1 ]
机构
[1] Capital Med Univ, Beijing Tongren Hosp, Dept Otorhinolaryngol Head & Neck Surg, Key Lab Otolaryngol Head & Neck Surg,Minist Educ, Beijing, Peoples R China
[2] Capital Med Univ, Beijing Chaoyang Hosp, Dept Otorhinolaryngol Head & Neck Surg, 1 Dong Jiao Min Xiang St, Beijing 100730, Peoples R China
来源
JOURNAL OF LARYNGOLOGY AND OTOLOGY | 2023年 / 137卷 / 09期
基金
中国国家自然科学基金;
关键词
Survival; Prognosis; Artificial Intelligence; Head And Neck Cancer; Machine Learning; CANCER; PROTEIN;
D O I
10.1017/S0022215123000063
中图分类号
R76 [耳鼻咽喉科学];
学科分类号
100213 ;
摘要
ObjectiveThis study aimed to establish a model for predicting the three-year survival status of patients with hypopharyngeal squamous cell carcinoma using artificial intelligence algorithms. MethodData from 295 patients with hypopharyngeal squamous cell carcinoma were analysed retrospectively. Training sets comprised 70 per cent of the data and test sets the remaining 30 per cent. A total of 22 clinical parameters were included as training features. In total, 12 different types of machine learning algorithms were used for model construction. Accuracy, sensitivity, specificity, area under the receiver operating characteristic curve and Cohen's kappa co-efficient were used to evaluate model performance. ResultsThe XGBoost algorithm achieved the best model performance. Accuracy, sensitivity, specificity, area under the receiver operating characteristic curve and kappa value of the model were 80.9 per cent, 92.6 per cent, 62.9 per cent, 77.7 per cent and 58.1 per cent, respectively. ConclusionThis study successfully identified a machine learning model for predicting three-year survival status for patients with hypopharyngeal squamous cell carcinoma that can offer a new prognostic evaluation method for the clinical treatment of these patients.
引用
收藏
页码:1041 / 1047
页数:7
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