Post-zygotic brain mosaicism as a result of partial reversion of pre-zygotic aneuploidy

被引：1
|
作者：
Chung, Changuk [1 ]
Yang, Xiaoxu [1 ]
Gleeson, Joseph G. [1 ]
机构：
[1] Univ Calif San Diego, Rady Childrens Inst Genom Med, Dept Neurosci, San Diego, CA 92103 USA
来源：
NATURE GENETICS | 2023年 / 55卷 / 11期
关键词：
D O I：
10.1038/s41588-023-01552-2
中图分类号：
Q3 [遗传学];
学科分类号：
071007 ; 090102 ;
摘要：
Brain somatic mosaicism is linked to several neurological disorders and is thought to arise post-zygotically. A study suggests that pre-zygotic aneuploidy followed by post-zygotic partial reversion leads to a recurrent form of brain mosaicism-related epilepsy.
引用
收藏
页码：1784 / 1785
页数：2
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