Second Oral SERD Shines in ER+ Breast Cancer

被引:3
|
作者
Pob, Alissa
机构
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D O I
10.1158/2159-8290.CD-NB2023-0005
中图分类号
R73 [肿瘤学];
学科分类号
100214 ;
摘要
The first data from the phase II SERENA-2 trial look promising for the investigational oral selective estrogen receptor degrader camizestrant. Compared with standard fulvestrant, it significantly prolonged progression-free survival in postmenopausal women with advanced estrogen receptor-positive, HER2-negative breast cancer. Camizestrant also bested fulvestrant in subgroup analyses of patients who previously received a CDK4/6 inhibitor, had visceral metastases, or had ESR1 mutations. ©2023 American Association for Cancer Research.
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