Synthesis and Application of Organic Hypervalent Bromine Reagents

In recent decades, with the rapid development of organic synthetic chemistry, organic hypervalent halogen reagents have drawn considerable research interest on the synthesis and application of organic hypervalent bromine reagents. Compared with traditional organic hypervalent iodine reagents, organic hypervalent bromine reagents have stronger oxidation capacity and reactivity, thus enabling their important application potential in organic synthesis. On the basis of different substituents of organic hypervalent bromine reagents, the diaryl-lambda(3)-bromanes, dialkyl-lambda(3)-bromanes, alkenyl-lambda(3)-bromanes, alkyne-lambda(3)-bromanes and heteroatomic-lambda(3)-bromanes are summarized and discussed successively. The synthetic methods of different types of hypervalent bromine reagents and their applications in organic reactions are also reviewed.