HIGH-THROUGHPUT METHOD TO ANALYZE THE CYTOTOXICITY OF CAR T CELLS IN A 3D TUMOR SPHEROID MODEL USING IMAGE CYTOMETRY

被引:0
|
作者
Lin, B. [1 ]
Zurowski, D. [2 ]
Patel, S. [1 ]
Hui, D. [2 ]
Ka, M. [2 ]
Hernandez, C. [1 ]
Love, A. [1 ]
Moore, A. [2 ]
Chan, L. [1 ]
机构
[1] Nexcelom PerkinElmer, Lawrence, MA USA
[2] Resilience, East Norriton, PA USA
关键词
CAR T cells; Image Cytometry; Cell-mediated cytotoxicity;
D O I
暂无
中图分类号
Q813 [细胞工程];
学科分类号
摘要
1008
引用
下载
收藏
页码:S216 / S216
页数:1
相关论文
共 50 条
  • [1] High-throughput method to analyze the cytotoxicity of CAR T cells in a 3D tumor spheroid model using image cytometry
    Patel, Samir
    Zurowski, David
    Hui, Daniel
    Ka, Mignane
    Hernandez, Charles
    Love, Andrea
    Lin, Bo
    Moore, Andrea
    Chan, Leo Li-Ying
    CANCER RESEARCH, 2023, 83 (07)
  • [2] High-Throughput Method to Analyze the Cytotoxicity of CAR T Cells in a 3D Tumor Spheroid Model Using Image Cytometry
    Zurowski, David
    Patel, Samir
    Hui, Daniel
    Ka, Mignane
    Hernandez, Charles
    Love, Andrea
    Lin, Bo
    Moore, Andrea
    Chan, Leo Li-Ying
    MOLECULAR THERAPY, 2023, 31 (04) : 430 - 430
  • [3] High-throughput method to analyze the cytotoxicity of CAR T Cells in a 3D tumor spheroid model using image cytometry
    Patel, Samir
    Zurowski, David
    Hui, Daniel
    Ka, Mignane
    Hernandez, Charles
    Love, Andrea
    Lin, Bo
    Moore, Andrea
    Chan, Leo Li-Ying
    JOURNAL OF IMMUNOLOGY, 2023, 210 (01):
  • [4] High-throughput method to analyze the cytotoxicity of CAR-T Cells in a 3D tumor spheroid model using image cytometry
    Zurowski, David
    Patel, Samir
    Hui, Daniel
    Ka, Mignane
    Hernandez, Charles
    Love, Andrea C.
    Lin, Bo
    Moore, Andrea
    Chan, Leo Li-Ying
    SLAS DISCOVERY, 2023, 28 (03) : 65 - 72
  • [5] High-Throughput 3D Tumor Spheroid Screening Method for Cancer Drug Discovery Using Celigo Image Cytometry
    Kessel, Sarah
    Cribbes, Scott
    Dery, Olivier
    Kuksin, Dmitry
    Sincoff, Eric
    Qiu, Jean
    Chan, Leo Li-Ying
    SLAS TECHNOLOGY, 2017, 22 (04): : 454 - 465
  • [6] 3D hanging spheroid plate for high-throughput CAR T cell cytotoxicity assay
    Zhenzhong Chen
    Seokgyu Han
    Arleen Sanny
    Dorothy Leung-Kwan Chan
    Danny van Noort
    Wanyoung Lim
    Andy Hee-Meng Tan
    Sungsu Park
    Journal of Nanobiotechnology, 20
  • [7] A high-throughput 3D tumor spheroid screening method for drug discovery using imaging cytometry
    Chan, Leo Li-Ying
    Cribbes, Scott
    Kessel, Sarah
    McMenemy, Scott
    Qiu, Jean
    CANCER RESEARCH, 2017, 77
  • [8] A high-throughput in vitro characterization method of CAR T cells using image cytometry
    Chan, Leo Li-Ying
    Maldini, Colby
    Love, Andrea
    Tosh, Kevin
    Gayout, Kevin
    Smith, Tim
    Riley, James
    CANCER RESEARCH, 2020, 80 (16)
  • [9] A HIGH-THROUGHPUT IN VITRO CHARACTERIZATION METHOD OF CAR T CELLS USING IMAGE CYTOMETRY
    Chan, L. L.
    Maldini, C.
    Love, A.
    Tosh, K.
    Gayout, K.
    Smith, T.
    Riley, J.
    CYTOTHERAPY, 2021, 23 (05) : S88 - S88
  • [10] A high-throughput image cytometry-based screening method for the cytotoxic effect of drug compounds on 3D tumor spheroid
    Chan, Leo Li-Ying
    Dery, Olivier
    Cribbes, Scott
    Kuksin, Dmitry
    Kessel, Sarah
    CANCER RESEARCH, 2016, 76