TNF-MK2 signaling drives protective autophagy following MAPK pathway inhibition in pancreatic cancer

被引：0
|
作者：
Khawar, Iftikhar Ali
Wei, Qing
Chen, Timothy Hung-Po
Lin, Lin
Grierson, Patrick M.
Lim, Kian-Huat
机构：
来源：
CANCER RESEARCH | 2023年 / 83卷 / 07期
关键词：
D O I：
10.1158/1538-7445.AM2023-3870
中图分类号：
R73 [肿瘤学];
学科分类号：
100214 ;
摘要：
3870
引用
收藏
页数：2
相关论文
共 50 条
  • [1] Inhibition of ERK MAPK signaling increases pancreatic cancer dependency on autophagy
    Bryant, Kirsten
    Peng, Sen
    Tikunov, Andrey
    Pierobon, Mariaelena
    Gunda, Venugopal
    Tomar, Garima
    Singh, Pankaj
    Petricoin, Emanuel
    Macdonald, Jeffrey
    Nhan Tran
    Kimmelman, Alec
    Der, Channing
    CANCER RESEARCH, 2018, 78 (13)
  • [2] Vertical inhibition of the autophagy pathway enhances sensitization to RAS MAPK pathway inhibition in pancreatic ductal adenocarcinoma
    Roach, Mallory K.
    DeLiberty, Jonathan M.
    Schechter, Elyse G.
    Yang, Runying
    Pieper, Noah L.
    Stalnecker, Clint A.
    Bryant, Kirsten L.
    CANCER RESEARCH, 2024, 84 (17)
  • [3] Suppression of pancreatic cancer proliferation through TXNIP-mediated inhibition of the MAPK signaling pathway
    Fei, Qinglin
    Jin, Kaizhou
    Shi, Saimeng
    Li, Tianjiao
    Guo, Duancheng
    Lin, Mengxiong
    Yu, Xianjun
    Wu, Weiding
    Ye, Longyun
    ACTA BIOCHIMICA ET BIOPHYSICA SINICA, 2024, 56 (04): : 513 - 524
  • [4] Qingyihuaji Formula promotes apoptosis and autophagy through inhibition of MAPK/ERK and PI3K/Akt/mTOR signaling pathway on pancreatic cancer in vivo and in vitro
    Qian, Xiang
    Bi, Qian-Yu
    Wang, Zeng-Na
    Han, Fang
    Liu, Lu-Ming
    Song, Li-Bin
    Li, Chang-Yu
    Zhang, Ai-Qin
    Ji, Xu-Ming
    JOURNAL OF ETHNOPHARMACOLOGY, 2023, 307
  • [5] Inhibition of Stat3 signaling pathway decreases TNF--induced autophagy in cementoblasts
    Wang, Leilei
    Wang, Yunlong
    Du, Mingyuan
    Liu, Zhijian
    Cao, Zhengguo
    Hao, Yunru
    He, Hong
    CELL AND TISSUE RESEARCH, 2018, 374 (03) : 567 - 575
  • [6] Inhibition of Stat3 signaling pathway decreases TNF-α-induced autophagy in cementoblasts
    Leilei Wang
    Yunlong Wang
    Mingyuan Du
    Zhijian Liu
    Zhengguo Cao
    Yunru Hao
    Hong He
    Cell and Tissue Research, 2018, 374 : 567 - 575
  • [7] Susceptibility to autophagy inhibition is enhanced by dual IGF1R and MAPK/ERK inhibition in pancreatic cancer
    Stalnecker, Clint A.
    Coleman, Michael F.
    Bryant, Kirsten L.
    AUTOPHAGY, 2022, 18 (07) : 1737 - 1739
  • [8] Inhibition of Hedgehog signaling pathway impedes cancer cell proliferation by promotion of autophagy
    Tang, Xiaoli
    Deng, Libin
    Chen, Qi
    Wang, Yao
    Xu, Rong
    Shi, Chao
    Shao, Jia
    Hu, Guohui
    Gao, Meng
    Rao, Hai
    Luo, Shiwen
    Lu, Quqin
    EUROPEAN JOURNAL OF CELL BIOLOGY, 2015, 94 (05) : 223 - 233
  • [9] Activation of autophagy, paraptosis, and ferroptosis by micheliolide through modulation of the MAPK signaling pathway in pancreatic and colon tumor cells
    Yang, Min Hee
    Baek, Seung Ho
    Jung, Young Yun
    Um, Jae-Young
    Ahn, Kwang Seok
    PATHOLOGY RESEARCH AND PRACTICE, 2024, 263
  • [10] Protective Role of Fucoidan in Cerebral Ischemia-Reperfusion Injury through Inhibition of MAPK Signaling Pathway
    Che, Nan
    Ma, Yijie
    Xin, Yinhu
    BIOMOLECULES & THERAPEUTICS, 2017, 25 (03) : 272 - 278
12345