Polygenic Germline Risk of Common Haematological Traits Drives Clonal Selection on JAK2 V617F and Development of Myeloproliferative Neoplasms

被引：0
|
作者：
Nangalia, Jyoti [1 ]
Guo, Jing [1 ]
Walter, Klaudia [1 ]
Quiros, Pedro [2 ]
Gu, Muxin [2 ]
Baxter, E. Joanna [3 ]
Danesh, John [4 ]
Di Angelantonio, Emanuele [4 ]
Roberts, David [4 ]
Guglielmelli, Paola [5 ,6 ]
Harrison, Claire N. [7 ]
Godfrey, Anna L. [8 ]
Green, Anthony R. [9 ]
Vassiliou, George [9 ]
Vuckovic, Dragana [10 ]
Soranzo, Nicole [11 ,12 ]
机构：
[1] Wellcome Sanger Inst, Hinxton, England
[2] Wellcome MRC Cambridge Stem Cell Inst, Cambridge, England
[3] Cambridge Univ Hosp NHS Fdn Trust, Dept Haematol, Cambridge, England
[4] Univ Cambridge, Natl Inst Hlth Res, Blood & Transplant Res Unit Donor Hlth & Gen, Cambridge, England
[5] AOU Careggi, Centro Ric & Innovazione Malattie Mieloproliferat, Florence, Italy
[6] Univ Florence, Dept Expt & Clin Med, Florence, Italy
[7] Guys & St Thomas NHS Fdn Trust, London, England
[8] Cambridge Univ Hosp NHS Trust, Cambridge, England
[9] Univ Cambridge, Wellcome MRC Cambridge Stem Cell Inst, Cambridge, England
[10] Imperial Coll London, London, England
[11] Wellcome Trust Sanger Inst, Wellcome Trust Genome Campus, Cambridge, England
[12] Human Technopole, Milan, Italy
来源：
BLOOD | 2023年 / 142卷
关键词：
D O I：
10.1182/blood-2023-189551
中图分类号：
R5 [内科学];
学科分类号：
1002 ; 100201 ;
摘要：
引用
收藏
页数：3
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