Elevated expression of CCN1 in dermal fibroblasts causes accelerated dermal aging and promotes keratinocyte carcinogenesis

被引:0
|
作者
Quan, T. [1 ]
Kim, A. [1 ]
Guo, C. [1 ]
Xiang, Y. [1 ]
Qin, Z. [1 ]
Liu, Y. [1 ]
Yan, Y. [1 ]
Ermilov, A. [1 ]
Voorhees, J. J. [1 ]
Dlugosz, A. [1 ]
Fisher, G. J. [1 ]
机构
[1] Univ Michigan, Dermatol, Ann Arbor, MI 48109 USA
关键词
D O I
暂无
中图分类号
R75 [皮肤病学与性病学];
学科分类号
100206 ;
摘要
363
引用
收藏
页码:S62 / S62
页数:1
相关论文
共 50 条
  • [1] Novel mouse model of skin aging: Expression of CCN1 in dermal fibroblasts drives dermal aging and promotes skin cancer development
    Quan, T.
    Qin, Z.
    Voorhees, J. J.
    Fisher, G. J.
    JOURNAL OF INVESTIGATIVE DERMATOLOGY, 2017, 137 (05) : S20 - S20
  • [2] Dermal Fibroblast CCN1 Expression in Mice Recapitulates Human Skin Dermal Aging
    Quan, Taihao
    Xiang, Yaping
    Liu, Yingchun
    Qin, Zhaoping
    Yang, Yan
    Bou-Gharios, George
    Voorhees, John J.
    Dlugosz, Andrzej A.
    Fisher, Gary J.
    JOURNAL OF INVESTIGATIVE DERMATOLOGY, 2021, 141 (04) : 1007 - 1016
  • [3] Expression of active matrix metalloproteinase-1 in dermal fibroblasts: A novel mouse model of accelerated human dermal aging
    He, T.
    Quan, T.
    Xia, W.
    Dlugosz, A. A.
    Voorhees, J. J.
    Fisher, G. J.
    JOURNAL OF INVESTIGATIVE DERMATOLOGY, 2021, 141 (05) : S31 - S31
  • [4] CCN1 contributes to skin connective tissue aging by inducing age-associated secretory phenotype in human skin dermal fibroblasts
    Quan, Taihao
    Qin, Zhaoping
    Robichaud, Patrick
    Voorhees, John J.
    Fisher, Gary J.
    JOURNAL OF CELL COMMUNICATION AND SIGNALING, 2011, 5 (03) : 201 - 207
  • [5] CCN1 contributes to skin connective tissue aging by inducing age-associated secretory phenotype in human skin dermal fibroblasts
    Taihao Quan
    Zhaoping Qin
    Patrick Robichaud
    John J. Voorhees
    Gary J. Fisher
    Journal of Cell Communication and Signaling, 2011, 5 : 201 - 207
  • [6] Keratinocyte Microvesicles Regulate the Expression of Multiple Genes in Dermal Fibroblasts
    Huang, Ping
    Bi, Jiarui
    Owen, Gethin R.
    Chen, Weimin
    Rokka, Anne
    Koivisto, Leeni
    Heino, Jyrki
    Haekkinen, Lari
    Larjava, Hannu
    JOURNAL OF INVESTIGATIVE DERMATOLOGY, 2015, 135 (12) : 3051 - 3059
  • [7] Elevated Cysteine-rich protein 61 (CYR61/CCN1) mediates down-regulation of collagen expression in senescent human dermal fibroblasts.
    Quan, T.
    Qin, Z.
    He, T.
    Voorhees, J. J.
    Fisher, C. J.
    JOURNAL OF INVESTIGATIVE DERMATOLOGY, 2011, 131 : S33 - S33
  • [8] Characterization of CCN1 functional domains that stimulate MMP-1 through integrin αVβ3 in human dermal fibroblasts
    Qin, Z.
    Robichaud, P.
    Voorhees, J. J.
    Fisher, G. J.
    Quan, T.
    JOURNAL OF INVESTIGATIVE DERMATOLOGY, 2012, 132 : S36 - S36
  • [9] Age-related dermal microenvironment promotes keratinocyte skin cancer development in mouse model of dermal aging
    Quan, T.
    Guo, C.
    Kim, J.
    Kim, A. J.
    Voorhees, J. J.
    Dlugosz, A.
    Fisher, G. J.
    JOURNAL OF INVESTIGATIVE DERMATOLOGY, 2024, 144 (08) : S19 - S19
  • [10] Keratinocyte-Conditioned Media Regulate Collagen Expression in Dermal Fibroblasts
    Ghaffari, Abdi
    Kilani, Ruhangiz T.
    Ghahary, Aziz
    JOURNAL OF INVESTIGATIVE DERMATOLOGY, 2009, 129 (02) : 340 - 347