A highly efficient, magnetite-supported and recyclable Pd catalyst for green C -C cross-coupling reactions

In the present study, an efficient, convenient, and green process for Suzuki-Miyaura and copper-free Sonogashira C -C coupling reactions catalyzed by the heterogenous catalyst [PdCl2{Ph2P)2N(CH2)3 Si(OMe)3 }] immobilized on Fe3O4 @SiO2 nanoparticles is described. The magnetic nanocatalyst, [PdCl2{Ph2P)2N(CH2)3Si(OMe)3 }]/Fe3O4 @SiO2 (2), was easily recovered with an external magnetic field and reused at least six times without noticeable leaching or loss of its catalytic activity. Furthermore, this eco-friendly methodology was developed using bio-solvents such as H2O/EtOH and microwave irra-diation ensuring short reaction times.& COPY; 2023 Elsevier B.V. All rights reserved.