A rare case of chordoma cutis

被引:0
|
作者
Jung, Dayeon [1 ]
Ko, Seung Min [1 ]
Seo, Jinwon [2 ]
Park, Eun Joo [1 ]
Kim, Kwang Joong [1 ]
Kim, Kwang Ho [1 ]
机构
[1] Hallym Univ, Sacred Heart Hosp, Dept Dermatol, 22 Gwanpyeong Ro 170beon Gil, Anyang 14068, Gyeonggi Do, South Korea
[2] Hallym Univ, Sacred Heart Hosp, Dept Pathol, Anyang, South Korea
关键词
brachyury; chordoma; chordoma cutis; malignancy; BRACHYURY EXPRESSION; TISSUE;
D O I
10.1111/cup.14525
中图分类号
R75 [皮肤病学与性病学];
学科分类号
100206 ;
摘要
Chordoma is a rare locally aggressive bone malignancy that originates from the notochord. It typically involves the sacrococcygeal area, spheno-occipital region of the skull, and spine. Cutaneous involvement of chordoma, termed as chordoma cutis, is uncommon and usually occurs via direct invasion or local recurrence. Distant metastasis to the skin is very rare. We report a case of chordoma cutis on the scalp, which lacked characteristic physaliferous cells but tested positive for brachyury, thus supporting the diagnosis of chordoma cutis. The patient, who presented with a solitary translucent nodule on the scalp, was previously diagnosed with chordoma on the vertebral column and skull 8 months prior. Microscopic examination showed a cord-like arrangement of plasmacytoid cells within a myxoid stroma. Physaliferous cells were not observed, and cytokeratin AE1/AE3 staining was negative; however, brachyury and epithelial membrane antigen staining was positive, leading to the diagnosis of chordoma cutis. Therefore, clinicians must include chordoma cutis in the differential diagnosis of translucent nodular lesions on the skin of patients formerly diagnosed with chordoma.
引用
收藏
页码:951 / 955
页数:5
相关论文
共 50 条
  • [1] Chordoma cutis, an unusual clinical presentation of a rare neoplasm: Chordoma
    Delteil, Clemence
    Malissen, Nausicaa
    Appay, Romain
    Magis, Quentin
    Aubert, Sebastien
    Bouvier, Corinne
    Richard, Marie-Aleth
    Macagno, Nicolas
    ANNALES DE PATHOLOGIE, 2018, 38 (02) : 126 - 130
  • [2] Chordoma cutis
    Boneschi, V
    Tourlaki, A
    Parafioriti, A
    Berti, E
    Brambati, M
    Brambilla, L
    EUROPEAN JOURNAL OF DERMATOLOGY, 2003, 13 (06) : 593 - 595
  • [3] Chordoma cutis
    Persichetti, Greg
    Walling, Hobart W.
    Rosen, Les
    Cronin, Terry, Jr.
    Ceilley, Roger I.
    DERMATOLOGIC SURGERY, 2007, 33 (12) : 1520 - 1524
  • [4] Chordoma cutis
    Rubin, AI
    Bagel, J
    Niedt, G
    JOURNAL OF THE AMERICAN ACADEMY OF DERMATOLOGY, 2005, 52 (05) : S105 - S108
  • [5] THE SACROCOCCYGEAL CHORDOMA - A RARE CASE
    CLOSSET, J
    MARISCAL, F
    HERIN, M
    ACTA CHIRURGICA BELGICA, 1986, 86 (03) : 163 - 165
  • [6] A Rare Case of Mediastinal Chordoma
    Albitar, H. A.
    Venkatesan, N.
    Ahluwalia, V.
    Petersen, I.
    Okuno, S.
    Rose, P.
    Iyer, V. N.
    AMERICAN JOURNAL OF RESPIRATORY AND CRITICAL CARE MEDICINE, 2023, 207
  • [7] CHORDOMA CUTIS - A REPORT OF 19 PATIENTS WITH CUTANEOUS INVOLVEMENT OF CHORDOMA
    SU, WPD
    LOUBACK, JB
    GAGNE, EJ
    SCHEITHAUER, BW
    JOURNAL OF THE AMERICAN ACADEMY OF DERMATOLOGY, 1993, 29 (01) : 63 - 66
  • [8] A Rare Case of Tuberculosis Cutis Colliquative
    Rimmalapudi, Shravya
    Morey, Amruta D.
    Madke, Bhushan
    Singh, Adarsh Lata
    Jawade, Sugat
    JOURNAL OF EVOLUTION OF MEDICAL AND DENTAL SCIENCES-JEMDS, 2021, 10 (05): : 305 - 307
  • [9] A rare case of aplasia cutis congenita
    Chen, Zhang
    Ning, Junjie
    ASIAN JOURNAL OF SURGERY, 2023, 46 (11) : 4848 - 4849
  • [10] Acral angioosteoma cutis: A rare case
    Erdogan-Durmus, Senay
    Ozekinci, Selver
    Yarikkaya, Enver
    Erzurumluoglu, Nurhan
    INDIAN JOURNAL OF DERMATOLOGY VENEREOLOGY & LEPROLOGY, 2018, 84 (06): : 685 - 686