Multicentric Reticulohistiocytosis-A rare and disabling disease

被引:2
|
作者
Ashaolu, Omowunmi [1 ]
Ng, Selwyn [2 ]
Smale, Shaun [3 ]
Hughes, Jenny [1 ]
机构
[1] Princess Wales Hosp, Dept Dermatol, Bridgend, Wales
[2] Morriston Hosp, Dept Histopathol, Swansea, Wales
[3] Princess Wales Hosp, Dept Rheumatol, Bridgend, Wales
来源
CLINICAL CASE REPORTS | 2023年 / 11卷 / 09期
关键词
arthritis mutilans; autoimmune disease; multicentric reticulohistiocytosis; non-langerhans cell histiocytosis; papulonodular skin lesion;
D O I
10.1002/ccr3.7846
中图分类号
R5 [内科学];
学科分类号
1002 ; 100201 ;
摘要
Key Clinical Message Multicentric reticulohistiocytosis is a rare multisystemic condition associated with papulonodular skin lesions, severe arthritis and malignancy. Histopathology shows histiocytes containing abundant eosinophilic ground glass cytoplasm and multinucleated giant cells. Early recognition, age-appropriate malignancy work-up and treatment is important to prevent impairment of daily life activity.
引用
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页数:3
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