Nickel-Catalyzed Reductive Three-Component Cross-Coupling of Butadiene with Aldehydes and Alkenyl Triflates/Bromides: Access to Skipped Dienes

被引：0
|
作者：
Xu, Yan [1 ]
Su, Tong [1 ]
Zhang, Jie-Rui [1 ]
Ding, Hua-Jiao [1 ]
Gao, Yuanji [1 ]
Xu, Minghui [1 ]
Cao, Peng [1 ]
Hu, Ping [1 ]
Wang, Bi-Qin [1 ]
Chen, Bin [1 ]
机构：
[1] Sichuan Normal Univ, Coll Chem & Mat Sci, Chengdu 610068, Peoples R China
来源：
ORGANIC LETTERS | 2023年 / 25卷 / 17期
关键词：
1,3-DIENES; HALIDES; ACIDS;
D O I：
10.1021/acs.orglett.3c01036
中图分类号：
O62 [有机化学];
学科分类号：
070303 ; 081704 ;
摘要：
A regio-and stereoselective nickel-catalyzed reductive three-component cross-coupling of 1,3-butadiene with aldehydes and alkenyl triflates or bromides was realized. This protocol afforded a convenient approach to the synthesis of skipped diene compounds bearing various functionals and heterocyclic groups. The utility of this reaction was also demonstrated by scale-up preparation and diverse transformations.
引用
收藏
页码：3136 / 3140
页数：5
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