DECREASED PREGNANE X RECEPTOR (PXR) EXPRESSION PROMOTES LIVER NODULE DEVELOPMENT IN Atp7b-/- MICE

被引：0
|
作者：
Wooton-Kee, Clavia R. [1 ]
Yalamanchili, Hari [1 ]
Moore, David D. [2 ]
机构：
[1] Baylor Coll Med, Houston, TX USA
[2] Univ Calif Berkeley, Berkeley, CA USA
来源：
HEPATOLOGY | 2023年 / 78卷
关键词：
D O I：
暂无
中图分类号：
R57 [消化系及腹部疾病];
学科分类号：
摘要：
199
引用
收藏
页码：S210 / S211
页数：2
相关论文
共 36 条
  • [1] Activation of Liver X Receptor/Retinoid X Receptor Pathway Ameliorates Liver Disease in Atp7B-/- (Wilson Disease) Mice
    Hamilton, James P.
    Koganti, Lahari
    Muchenditsi, Abigael
    Pendyala, Venkata S.
    Huso, David
    Hankin, Joseph
    Murphy, Robert C.
    Huster, Dominik
    Merle, Uta
    Mangels, Christopher
    Yang, Nan
    Potter, James J.
    Mezey, Esteban
    Lutsenko, Svetlana
    HEPATOLOGY, 2016, 63 (06) : 1828 - 1841
  • [2] Decreased Nuclear Receptor Activity in the Atp7b-/- Mice (Wilson's disease mouse)
    Wooton-Kee, Clavia R.
    Moore, David D.
    HEPATOLOGY, 2012, 56 : 315A - 315A
  • [3] DECREASED PREGNANE X RECEPTOR (PXR) EXPRESSION IN CHILDREN WITH CROHN'S DISEASE
    Shakhnovich, V.
    Vyhlidal, C. A.
    Friesen, C.
    Hildreth, A.
    Daniel, J.
    Singh, V.
    Kearns, G. L.
    Leeder, S. J.
    CLINICAL PHARMACOLOGY & THERAPEUTICS, 2014, 95 : S13 - S13
  • [4] Interleukin (IL)-6 downregulates expression of the pregnane X receptor (PXR) in mice.
    Hartmann, G
    Jekerle, V
    Piquette-Miller, M
    CLINICAL PHARMACOLOGY & THERAPEUTICS, 2003, 73 (02) : P60 - P60
  • [5] The influence of the long-term chemical activation of the nuclear receptor pregnane X receptor (PXR) on liver carcinogenesis in mice
    Shizu, Ryota
    Ishimura, Mai
    Nobusawa, Sumihito
    Hosaka, Takuomi
    Sasaki, Takamitsu
    Kakizaki, Satoru
    Yoshinari, Kouichi
    ARCHIVES OF TOXICOLOGY, 2021, 95 (03) : 1089 - 1102
  • [6] The influence of the long-term chemical activation of the nuclear receptor pregnane X receptor (PXR) on liver carcinogenesis in mice
    Ryota Shizu
    Mai Ishimura
    Sumihito Nobusawa
    Takuomi Hosaka
    Takamitsu Sasaki
    Satoru Kakizaki
    Kouichi Yoshinari
    Archives of Toxicology, 2021, 95 : 1089 - 1102
  • [7] A mechanism for the anti-fibrogenic effects of the pregnane X receptor (PXR) in the liver:: Inhibition of NF-κB?
    Axon, A.
    Cowie, D. E.
    Mann, D. A.
    Wright, M. C.
    TOXICOLOGY, 2008, 246 (01) : 40 - 44
  • [8] Histological features of liver disease development in the Atp7b-/- mouse: a model of Wilson's disease
    Lavrut, Pierre-Marie
    Guillaud, Olivier
    Dumortier, Jerome
    Mintz, Elisabeth
    Brun, Virginie
    Heissat, Sophie
    Bedoya, Eduardo Couchonnal
    Lachaux, Alain
    Bost, Muriel
    Hervieu, Valerie
    JOURNAL OF CLINICAL PATHOLOGY, 2023,
  • [9] Treatment with the LXR agonist T0901317 ameliorates liver disease in Atp7b-/- (Wilson Disease) mice
    Hamilton, James P.
    Koganti, Lahari
    Potter, James J.
    Muchenditsi, Abigael
    Huso, David L.
    Mezey, Esteban
    Lutsenko, Svetlana
    HEPATOLOGY, 2014, 60 : 275A - 275A
  • [10] Pregnane X receptor promotes liver enlargement in mice through the spatial induction of hepatocyte hypertrophy and proliferation
    Tian, Jianing
    Wang, Ruimin
    Yang, Xiao
    Yang, Jie
    Zhang, Yifei
    Li, Xuan
    Liang, Hangfei
    Fan, Shicheng
    Gao, Yue
    Zhang, Simin
    Qu, Xiangyang
    Huang, Min
    Bi, Huichang
    CHEMICO-BIOLOGICAL INTERACTIONS, 2022, 367
1234