Research Progress of Sulfur Dioxide Fluorescent Probe Targeting Mitochondria

Content of abstract sulfur dioxide (SO2) is associated with many physiological and pathological processes in living systems, and excessive SO2 can lead to a series of physiological diseases. Therefore, effective identification and detection of SO2 have significant application value. Recently, many fluorescent probes for the detection of SO2 in biological systems have been reported. Compared with traditional detection methods, fluorescent probe has the advantages of high sensitivity, non-invasive detection and real-time imaging. More importantly, the use of fluorescent probes allows visual detection of SO2 both in vitro and in vivo. Based on different reaction mechanism, the research progress of mitochondrial targeted SO2 fluorescent probes in the past five years is reviewed, and the challenges and development directions in this field are discussed.