Direct Determination of Kynurenic Acid with HPLC-MS/MS Method in Honey

被引：0
|
作者：
Pavlin, Anze
Pompe, Matevz
Kocar, Drago [1 ]
机构：
[1] Univ Ljubljana, Fac Chem & Chem Technol, Dept Chem & Biochem, Vecna pot 113, SI-1000 Ljubljana, Slovenia
来源：
ACTA CHIMICA SLOVENICA | 2023年 / 70卷 / 02期
关键词：
Kynurenic acid; honey; HPLC-MS; MS; SRM; TRYPTOPHAN; LIGAND;
D O I：
10.17344/acsi.2023.8079
中图分类号：
O6 [化学];
学科分类号：
0703 ;
摘要：
Kynurenic acid (KYNA) has been attributed many beneficial properties, such as antioxidant, antiproliferative, anti-inflammatory, and anti-obesogenic, as it is believed to affect metabolism and weight gain. A rapid and simple HPLC-MS/ MS method for the determination of kynurenic acid (KYNA) in honey has been developed. HPLC-MS/MS system allowed us to perform the analyzes without any special extraction or treatment of the samples. The study was carried out on different honeys: Chestnut (C), Linden (L), Acacia (A), Spruce (S), Silver Fir (SF), Forest (Fo) and Flower (F). The highest mean concentration, 682 & mu;g/g, was determined for chestnut honey, making it one of the foods with the highest KYNA content.
引用
收藏
页码：274 / 280
页数：7
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