Early Intervention and Favorable Biologic Effects of Personalized Neoantigen Vaccines on the Tumor Immune Microenvironment in Smoldering Waldenstrom Macroglobulinemia

被引：1

作者：

Szymura, Szymon ^{[1
]}

Cha, Soungchul ^{[1
]}

Wang, Lin ^{[1
]}

Zhang, Tiantian ^{[1
]}

Dong, Zhenyuan ^{[1
]}

Anderson, Aaron ^{[1
]}

Oh, Elizabeth ^{[1
]}

Wang, Zhe ^{[1
]}

Lee, Vincent ^{[1
]}

Parshottham, Sapna ^{[2
]}

Rao, Sheetal ^{[3
]}

Olsem, Jasper B. ^{[2
]}

Crumpton, Brandon N. ^{[2
]}

Lee, Hans C. ^{[4
]}

Manasanch, Elisabet E. ^{[5
]}

Neelapu, Sattva S.

Thomas, Sheeba K. ^{[5
]}

Kwak, Larry W. ^{[6
]}

机构：

[1] City Hope Natl Med Ctr, Duarte, CA USA

[2] MD Anderson Canc Ctr, Houston, TX USA

[3] UT MD Anderson Canc Ctr, Houston, TX USA

[4] MD Anderson Canc Ctr, Dept Lymphoma Myeloma, Houston, TX USA

[5] Univ Texas MD Anderson Canc Ctr, Dept Lymphoma & Myeloma, Houston, TX USA

[6] City Hope Natl Med Ctr, Beckman Inst, Stephenson Lymphoma Ctr, Duarte, CA USA

来源：

BLOOD | 2023年 / 142卷

关键词：

D O I：

10.1182/blood-2023-182448

中图分类号：

R5 [内科学];

学科分类号：

1002 ; 100201 ;

摘要：

引用

页数：4

共 4 条

[1] A Novel Therapeutic DNA Vaccine Elicits Reduction of Tumor Clones and Favorable Perturbations in the Immune Microenvironment in Patients (pts) with Untreated Smoldering Waldenstrom Macroglobulinemia (sWM)
Thomas, Sheeba K.
Cha, Soung-Chul
Parshottam, Sapna R.
Rao, Sheetal S.
Olsem, Jasper B.
Crumpton, Brandon N.
Szymura, Szymon
Wang, Zhe
Anderson, Aaron
Feng, Lei
Lee, Hans C.
Manasanch, Elisabet E.
Patel, Krina K.
Weber, Donna M.
Orlowski, Robert Z.
Neelapu, Sattva S.
Kwak, Larry W.
BLOOD, 2020, 136
[2] Dysfunctions of innate and adaptive immune tumor microenvironment in Waldenstrom macroglobulinemia
Cholujova, Danka
Beke, Gabor
Hunter, Zachary R.
Hideshima, Teru
Flores, Ludmila
Zeleznikova, Tatiana
Harrachova, Denisa
Klucar, Lubos
Leiba, Merav
Drgona, Lubos
Treon, Steven P.
Kastritis, Efstathios
Dorfman, David M.
Anderson, Kenneth C.
Jakubikova, Jana
INTERNATIONAL JOURNAL OF CANCER, 2023, 152 (09) : 1947 - 1963
[3] High-Dimensional Heterogeneity of Waldenstrom Macroglobulinemia within Its Immune Tumor Microenvironment
Jakubikova, Jana
Cholujova, Danka
Beke, Gabor
Hunter, Zachary R.
Hideshima, Teru
Flores, Ludmila
Leiba, Merav
Richardson, Paul G.
Kastritis, Eftathios
Dorfman, David M.
Treon, Steven P.
Anderson, Kenneth C.
BLOOD, 2019, 134
[4] Personalized neoantigen vaccines as early intervention in untreated patients with lymphoplasmacytic lymphoma: a non-randomized phase 1 trial
Szymura, Szymon J.
Wang, Lin
Zhang, Tiantian
Cha, Soung-chul
Song, Joo
Dong, Zhenyuan
Anderson, Aaron
Oh, Elizabeth
Lee, Vincent
Wang, Zhe
Parshottam, Sapna
Rao, Sheetal
Olsem, Jasper B.
Crumpton, Brandon N.
Lee, Hans C.
Manasanch, Elisabet E.
Neelapu, Sattva
Kwak, Larry W.
Thomas, Sheeba K.
NATURE COMMUNICATIONS, 2024, 15 (01)

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