The PNPLA3 I148M variant aggravates inflammation through dysfunctional LXR and PPAR gamma signalling in macrophages

被引:0
|
作者
Dixon, Emmanuel Dauda [1 ]
Claudel, Thierry [1 ]
Genger, Jakob-Wendelin [2 ,3 ]
Zhu, Ci [4 ]
Paolini, Erika [5 ,6 ]
Nardo, Alexander D. [1 ]
Stadlmayr, Sarah [7 ]
Mlitz, Veronika [1 ]
Fuchs, Claudia [1 ]
Radtke, Christine [7 ]
Bergthaler, Andreas [8 ]
Dongiovanni, Paola [5 ,6 ]
Ellmeier, Wilfried [4 ]
Trauner, Michael [1 ]
机构
[1] Med Univ Vienna, Div Gastroenterol & Hepatol, Hans Popper Lab Mol Hepatolog, Internal Med 3, Vienna, Austria
[2] Med Univ Vienna, Vienna, Austria
[3] Ctr Pathophysiol Infectiol & Immunol, Vienna, Austria
[4] Med Univ Vienna, Inst Immunol, Vienna, Austria
[5] Fdn IRCCS Ca Granda Osped Maggiore Policlin, Milan, Italy
[6] Univ Studi Milano, Dept Pharmacol & Biomol Sci, Milan, Italy
[7] Med Univ Vienna, Dept Plast Reconstruct & Aesthet Surg, Vienna, Austria
[8] CeMM Forschungszentrum Mol Med GmbH, Ctr Pathophysiol Infectiol & Immunol, Vienna, Austria
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中图分类号
R57 [消化系及腹部疾病];
学科分类号
摘要
WED-418
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页码:S746 / S747
页数:2
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