A New 1,2-Seco-Flavan-3-ol from the Leaves of Cinnamomum camphora var. linaloolifera

被引：0
|
作者：
Zhang, Yao [1 ]
Liu, Shilin [1 ]
Chen, Yuanan [1 ]
Niu, Zeyue [1 ]
Wu, Kaiwen [1 ]
Wu, Meiting [1 ]
Zhang, Xiaoqin [2 ]
Ni, Lin [1 ,3 ]
机构：
[1] Fujian Agr & Forestry Univ, Coll Plant Protect, Fuzhou 350002, Peoples R China
[2] Fujian Univ Tradit Chinese Med, Coll Pharm, Fuzhou 350122, Peoples R China
[3] Fujian Coll & Univ, Engn Res Inst Conservat & Utilizat Nat Bioresourc, Fuzhou 350002, Peoples R China
来源：
CHEMISTRY OF NATURAL COMPOUNDS | 2023年 / 59卷 / 03期
关键词：
Cinnamomum; chemical constituents; flavanols; HepG2; CONSTITUENTS;
D O I：
10.1007/s10600-023-04021-8
中图分类号：
R914 [药物化学];
学科分类号：
100701 ;
摘要：
A new 1,2-seco-flavan-3-ol,(2S)-1-(3 ''-methoxy-4 ''-hydroxyphenyl)-3-(2 ',6 '-dimethoxy-4 '-hydroxyphenyl)-propan-2-ol (1), together with nine known compounds (2-10) were isolated from the leaves of Cinnamomum camphora var. linaloolifera Y. Fujita. Their structures were identified by spectroscopic methods and comparison with reported references. Compounds 1, 2, and 7 have different degrees of inhibition on HepG2 cells, IC50 values vary between 50 and 110 mu mol center dot L-1.
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收藏
页码：451 / 454
页数：4
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