Impact of obesity on outcomes after surgical stabilization of multiple rib fractures: Evidence from the US nationwide inpatient sample

被引:1
|
作者
Liu, Yang-Fan [1 ,2 ,3 ,4 ]
Chen, Te-Li [5 ]
Tseng, Ching-Hsueh [5 ]
Wang, Jen-Yu [5 ]
Wang, Wen-Ching [2 ,3 ]
机构
[1] Hsinchu MacKay Mem Hosp, Dept Thorac Surg, Hsinchu, Taiwan
[2] Natl Tsing Hua Univ, Dept Life Sci, Hsinchu, Taiwan
[3] Natl Tsing Hua Univ, Inst Mol & Cellular Biol, Hsinchu, Taiwan
[4] Natl Tsing Hua Univ, Int Intercollegiate PhD Programme, Hsinchu, Taiwan
[5] Hsinchu MacKay Mem Hosp, Dept Emergency, Hsinchu, Taiwan
来源
PLOS ONE | 2024年 / 19卷 / 02期
关键词
ACUTE KIDNEY INJURY; BODY-MASS INDEX; COMPLICATIONS; RISK; MORTALITY;
D O I
10.1371/journal.pone.0299256
中图分类号
O [数理科学和化学]; P [天文学、地球科学]; Q [生物科学]; N [自然科学总论];
学科分类号
07 ; 0710 ; 09 ;
摘要
Background Obesity is a global health issue with increasing prevalence. Surgical procedures, such as surgical stabilization of rib fractures (SSRF), may be affected by obesity-related complications. The objective of the study is to investigate the effects of obesity on SSRF outcomes in multiple rib fractures. Methods This retrospective study analyzed data from adults aged >= 20 years in the Nationwide Inpatient Sample (NIS) database diagnosed with multiple rib fractures who underwent SSRF between 2005 and 2018. It investigated the relationship between obesity and in-patient outcomes, such as discharge status, length of stay (LOS), in-hospital mortality, hospital costs, and adverse events using logistic and linear regression analyses. Results Analysis of data from 1,754 patients (morbidly obese: 87; obese: 106; normal weight: 1,561) revealed that morbid obesity was associated with longer LOS (aBeta = 0.07, 95% CI: 0.06, 0.07), higher hospital costs (aBeta = 47.35, 95% CI: 38.55, 56.14), increased risks of adverse events (aOR = 1.63, 95% CI: 1.02, 2.61), hemorrhage/need for transfusion (aOR = 1.77, 95% CI: 1.12, 2.79) and mechanical ventilation >= 96 hours (aOR = 2.14, 95% CI: 1.28, 3.58) compared to normal weight patients. Among patients with flail chest, morbid obesity was significantly associated with tracheostomy (aOR = 2.13, 95% CI: 1.05, 4.32), ARDS/respiratory failure (aOR = 2.01, 95% CI: 1.09, 3.70), and mechanical ventilation >= 96 hours (aOR = 2.80, 95% CI: 1.47, 5.32). In contrast, morbid obesity had no significant associations with these adverse respiratory outcomes among patients without a flail chest (p > 0.05). Conclusions Morbid obesity is associated with adverse outcomes following SSRF for multiple rib fractures, especially for flail chest patients.
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页数:15
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