Antioxidant and Antidiabetic Activity of Algae

被引:20
|
作者
Abo-Shady, Atef Mohamed [1 ]
Gheda, Saly Farouk [1 ]
Ismail, Gehan Ahmed [1 ]
Cotas, Joao [2 ]
Pereira, Leonel [2 ]
Abdel-Karim, Omnia Hamdy [1 ,3 ]
机构
[1] Tanta Univ, Fac Sci, Bot Dept, Tanta 31527, Egypt
[2] Univ Coimbra, MARE Marine & Environm Sci Ctr, Dept Life Sci, ARNET Aquat Res Network, P-3000456 Coimbra, Portugal
[3] Wageningen Univ & Res, Bioproc Engn & AlgaePARC, NL-6700 AA Wageningen, Netherlands
来源
LIFE-BASEL | 2023年 / 13卷 / 02期
关键词
diabetes; antioxidant; antihyperglycemic; lipid profile; body weight; algal treatments; SPIRULINA-PLATENSIS; ALPHA-AMYLASE; OXIDATIVE STRESS; IN-VITRO; ANTIMICROBIAL ACTIVITY; INHIBITORY-ACTIVITIES; BIOACTIVE COMPOUNDS; MICROALGAE; SEAWEEDS; EXTRACT;
D O I
10.3390/life13020460
中图分类号
Q [生物科学];
学科分类号
07 ; 0710 ; 09 ;
摘要
Currently, algae arouse a growing interest in the pharmaceutical and cosmetic area due to the fact that they have a great diversity of bioactive compounds with the potential for pharmacological and nutraceutical applications. Due to lifestyle modifications brought on by rapid urbanization, diabetes mellitus, a metabolic illness, is the third largest cause of death globally. The hunt for an efficient natural-based antidiabetic therapy is crucial to battling diabetes and the associated consequences due to the unfavorable side effects of currently available antidiabetic medications. Finding the possible advantages of algae for the control of diabetes is crucial for the creation of natural drugs. Many of algae's metabolic processes produce bioactive secondary metabolites, which give algae their diverse chemical and biological features. Numerous studies have demonstrated the antioxidant and antidiabetic benefits of algae, mostly by blocking carbohydrate hydrolyzing enzyme activity, such as alpha-amylase and alpha-glucosidase. Additionally, bioactive components from algae can lessen diabetic symptoms in vivo. Therefore, the current review concentrates on the role of various secondary bioactive substances found naturally in algae and their potential as antioxidants and antidiabetic materials, as well as the urgent need to apply these substances in the pharmaceutical industry.
引用
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页数:26
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