The role of circular RNA in tumor microenvironment and immunotherapy

被引：4

作者：

He, Yu ^{[1
]}

Huang, Qiu ^{[1
]}

Ge, Yue ^{[1
]}

Liu, Xiao ^{[1
]}

Tong, Yonghua ^{[1
]}

Shang, Haojie ^{[1
]}

Xia, Ding ^{[1
]}

Peng, Ejun ^{[1
]}

Wu, Jian ^{[1
]}

Chen, Zhiqiang ^{[1
]}

Tang, Kun ^{[1
]}

机构：

[1] Huazhong Univ Sci & Technol, Tongji Hosp, Tongji Med Coll, Dept Urol, Wuhan, Peoples R China

来源：

INTERNATIONAL JOURNAL OF BIOLOGICAL MACROMOLECULES | 2023年 / 242卷

基金：

中国国家自然科学基金; 海南省自然科学基金;

关键词：

circRNAs; Tumor microenvironment; Immunotherapy; cancer; CANCER-IMMUNOTHERAPY; LUNG-CANCER; VACCINES; EXPRESSION; RESISTANCE; CIRCRNA; HETEROGENEITY; MECHANISMS; BIOMARKER; IMMUNITY;

D O I：

10.1016/j.ijbiomac.2023.124929

中图分类号：

Q5 [生物化学]; Q7 [分子生物学];

学科分类号：

071010 ; 081704 ;

摘要：

Cancer immunotherapy has favorable efficacy in various types of tumors, and has become an important weapon in the treatment of tumors in recent years. Long noncoding RNAs and microRNAs have been identified to play important roles in regulating cancer immunotherapy. Circular RNAs (circRNAs) are involved in the pathological process of many diseases, especially cancer. Many functions of circRNAs have been extensively studied. How-ever, the functions of circRNAs in the tumor microenvironment and cancer immunotherapy do not appear to be fully elucidated. Therefore, we review the roles of circRNAs in tumor microenvironment and cancer immunotherapy.

引用

页数：13

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