Chronic Ulcer on the Tongue as a Manifestation of Histoplasmosis During Anti-tumor Necrosis Factor-Alpha (TNF-α) Inhibitor Therapy for Psoriasis

被引：0
|
作者：
Harrison, Iris [1 ]
Forouzandeh, Mahtab [1 ]
Motaparthi, Kiran [1 ]
机构：
[1] Univ Florida, Dept Dermatol, Coll Med, Gainesville, FL 32610 USA
来源：
CUREUS JOURNAL OF MEDICAL SCIENCE | 2023年 / 15卷 / 09期
关键词：
tumor necrosis factor-alpha; adalimumab; granuloma; ulcer; tongue; histoplasmosis; COMPLICATION; SARCOIDOSIS; EFFICACY; FEATURES; SAFETY;
D O I：
10.7759/cureus.45217
中图分类号：
R5 [内科学];
学科分类号：
1002 ; 100201 ;
摘要：
Anti-tumor necrosis factor-alpha (TNF-alpha) inhibitors are commonly used in the treatment of inflammatory conditions such as psoriasis. However, these agents lead to increased susceptibility to infections. We report a patient with reactivation of latent histoplasmosis six months after starting an anti-TNF-alpha inhibitor for the treatment of psoriasis. Dermatologists should be aware of the risks associated with initiating therapy and maintain a low threshold of suspicion for this infection in patients on anti-TNF-alpha inhibitors presenting with oral ulcers.
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页数：6
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