Oligometastatic Hormone-Sensitive Prostate Cancer. Why Radiotherapy?

被引:3
|
作者
Los Arcos, Marta Barrado [1 ,2 ]
Lopez-Campos, Fernando [3 ]
Valcarcel, Marta Lopez [4 ]
Rubio, Manuel Galdeano [5 ]
de Manzanos, Ignacio Visus Fernandez [1 ,2 ]
Duque-Santana, Victor [3 ]
Aparicio, Marian Gomez [6 ]
Martin, Juan Zafra [7 ,8 ]
Kishan, Amar U. [9 ,10 ]
Achard, Verane [11 ,12 ]
Siva, Shankar [13 ,14 ]
Counago, Felipe [15 ]
机构
[1] Hosp Univ Navarra, Pamplona, Navarra, Spain
[2] Inst Invest Navarra IdiSNA, Pamplona, Navarra, Spain
[3] Hosp Univ Ramon y Cajal, Madrid, Spain
[4] Hosp Univ Puerta Hierro, Madrid, Spain
[5] Hosp Terrassa Consorci Sanitari Terrassa, Terrassa, Cataluna, Spain
[6] Hosp Gen Univ Toledo, Toledo, Spain
[7] Hosp Univ Virgen Victoria, Malaga, Spain
[8] Univ Granada, Granada, Spain
[9] Univ Calif Los Angeles, Los Angeles, CA USA
[10] UCLA, Dept Radiat Oncol, Los Angeles, CA USA
[11] Hop Fribourgeois HFR Freiburger Spital HFR, Fribourg, Switzerland
[12] HUG Hop Univ Geneve, Geneva, Switzerland
[13] Peter Maallum Canc Ctr, Melbourne, Australia
[14] Univ Melbourne, Melbourne, Australia
[15] Genesis Care, La Milagrosa Hosp, San Francisco de Asis Hosp, Natl Chair Res & Clin Trials, Madrid, Spain
关键词
Metastasis-directed therapy; Metastatic prostate cancer; Radiotherapy; METASTASIS-DIRECTED THERAPY; PHASE-II TRIAL; BODY RADIOTHERAPY; MULTICENTER; RECURRENCE; SURVEILLANCE; PROGRESSION; STOMP;
D O I
10.1016/j.clgc.2022.10.015
中图分类号
R73 [肿瘤学];
学科分类号
100214 ;
摘要
Androgen deprivation therapy (ADT) has been considered for years the standard initial treatment for patients with metastatic prostate cancer (mPC). Recently published results support the use of taxanes, second-generation antian-drogens or radiotherapy to the primary tumor as part of the treatment in these patients, considering ADT alone as suboptimal. Metastasis-directed therapy (MDT) is used as part of the treatment for oligometastatic patients in differ-ent tumor types. In oligometastatic hormone-sensitive prostate cancer the role of MDT is being studied with promising results. In the present review we assess the available evidence for radiotherapy to the primary tumor in newly diagnosed mPC and for MDT in oligometastatic prostate cancer, as well as future directions in this clinical setting.
引用
收藏
页码:E93 / E103
页数:11
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