Electrochemically enabled C(sp3)-C(sp) cross-coupling of alkyl iodides, N-hydroxyphthalimide esters, and Katritzky salts with acetylenic sulfones

被引：3

作者：

Yin, Jiawen ^{[1
]}

Zhang, Xiao ^{[1
]}

Zhao, Lulu ^{[1
]}

Luo, Mengqi ^{[1
]}

Guo, Lin ^{[1
]}

Yang, Chao ^{[1
]}

Xia, Wujiong ^{[1
,2
]}

机构：

[1] Harbin Inst Technol Shenzhen, Sch Sci, State Key Lab Urban Water Resource & Environm, Shenzhen 518055, Peoples R China

[2] Henan Normal Univ, Sch Chem & Chem Engn, Xinxiang 453007, Henan, Peoples R China

来源：

ORGANIC CHEMISTRY FRONTIERS | 2023年 / 10卷 / 18期

关键词：

CATALYZED DECARBOXYLATIVE ALKYNYLATION; C-H BONDS; TERMINAL ALKYNES; SONOGASHIRA REACTIONS; CARBOXYLIC-ACIDS; GRIGNARD-REAGENTS; ROOM-TEMPERATURE; BROMIDES; EFFICIENT; HALIDES;

D O I：

10.1039/d3qo00844d

中图分类号：

O62 [有机化学];

学科分类号：

070303 ; 081704 ;

摘要：

An electrochemically enabled C(sp(3))-C(sp) cross-coupling reaction is herein described for the synthesis of internal alkynes. This method is suitable not only for a diverse range of acetylenic sulfones, but also for a wide range of alkyl radical precursors, such as alkyl iodides, N-hydroxyphthalimide esters and Katritzky salts. This method can also be applied to vinylation, thioetherification, selenation and hydrogenation reactions. This reaction has a lot of significant advantages such as mild conditions, broad functional group tolerance, simple operation and easy purification and scale-up.

引用

页码：4679 / 4686

页数：8

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