Host-microbial crosstalk relies on "tuft"love

被引：0
|
作者：
De Santis, Stefania [1 ]
Pizarro, Theresa T. [1 ]
机构：
[1] Case Western Reserve Univ, Sch Med, Dept Pathol, Cleveland, OH 44106 USA
来源：
IMMUNITY | 2024年 / 57卷 / 02期
关键词：
TRIGGERS;
D O I：
10.1016/j.immuni.2024.01.016
中图分类号：
R392 [医学免疫学]; Q939.91 [免疫学];
学科分类号：
100102 ;
摘要：
How commensals influence intestinal immunity is incompletely understood. In this issue of Immunity, Eshleman et al. demonstrate that microbiota-derived butyrate restrains tuft cell development via HDAC3 modulation in intestinal epithelial cells, showing how microbial metabolites impact intestinal type 2 immunity.
引用
收藏
页码：195 / 197
页数：3
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