Removal of circulating nucleosomes/neutrophil extracellular traps (NETs) reduces ex-situ reperfusion injury in porcine DCD livers preserved with normothermic machine perfusion (NMP)

被引：0
|
作者：
Dengu, F. [1 ]
Abbas, H. [1 ]
Schofield, J. [2 ]
Morovat, R. [3 ]
Quaglia, A. [4 ]
Pamart, D. [5 ]
Candiracci, J. [5 ]
Micallef, J. [5 ]
Herzog, M. [5 ]
Wang, G. [2 ]
Abrams, S. [2 ]
Toh, C. -H. [2 ]
Aswani, A. [6 ]
Friend, P. [1 ]
机构：
[1] Univ Oxford, Nuffield Dept Surg Sci, Oxford, England
[2] Univ Liverpool, Dept Clin Infect Microbiol & Immunol, Liverpool, Merseyside, England
[3] Oxford Univ Hosp NHS Trust, Clin Biochem, Oxford, England
[4] UCL, Fac Med Sci, London, England
[5] Belgian Volit SRL, Isnes, Belgium
[6] Santersus AG, Zurich, Switzerland
来源：
TRANSPLANTATION | 2023年 / 107卷 / 09期
关键词：
D O I：
暂无
中图分类号：
R392 [医学免疫学]; Q939.91 [免疫学];
学科分类号：
100102 ;
摘要：
eP-051
引用
收藏
页码：123 / 124
页数：2
相关论文
共 12 条
  • [1] Removal of Circulating Nucleosomes/Neutrophil Extracellular Traps (nets) Reduces Ex-Situ Reperfusion Injury in Porcine Dcd Livers Preserved with Normothermic Machine Perfusion (nmp)
    Dengu, F.
    Abbas, H.
    Schofield, J.
    Morovat, R.
    Quaglia, A.
    Wang, G.
    Abrams, S.
    Micallef, J.
    Herzog, M.
    Candiracci, J.
    Toh, C.
    Aswani, A.
    Friend, P.
    AMERICAN JOURNAL OF TRANSPLANTATION, 2023, 23 (06) : S474 - S475
  • [2] Optimisation of donation after circulatory death (DCD) livers removal of extracellular histones during normothermic perfusion and following whole blood reperfusion in an ex-situ porcine model
    Abbas, S. H.
    Dengu, F.
    Schofield, J.
    Wang, G.
    Morovat, A.
    Quaglia, A.
    Abrams, S.
    Toh, C. -H.
    Aswani, A.
    Friend, P.
    LIVER TRANSPLANTATION, 2024, 30 : 37 - 38
  • [3] Circulating Neutrophil Extracellular Traps (NETs) in deceased donors prior to retrieval and during normothermic perfusion an opportunity for donor liver optimisation in-situ, ex-situ and beyond
    Abbas, S. H.
    Dengu, F.
    Ceresa, C.
    Aswani, A.
    Friend, P.
    LIVER TRANSPLANTATION, 2024, 30 : 180 - 181
  • [4] Ex-Situ Reperfusion Injury/Inflammation: Immuno-Molecular Profiling of Human Livers During Normothermic Machine Perfusion
    Dengu, F.
    Critchley, W.
    Abbas, H.
    Ceresa, C.
    Lo Faro, M.
    Stone, J.
    Aswani, A.
    Coussios, C.
    Ploeg, R.
    Nasralla, D.
    Fildes, J.
    Friend, P.
    AMERICAN JOURNAL OF TRANSPLANTATION, 2023, 23 (06) : S1085 - S1085
  • [5] Circulating neutrophil extracellular traps (NETs) in deceased donors prior to retrieval and during normothermic perfusion - An opportunity for donor liver optimisation in-situ, ex-situ and beyond.
    Hussain Abbas, Syed
    Dengu, Funga
    Sadik, Hatem
    Ceresa, Carlo
    Aswani, Andrew
    Friend, Peter
    TRANSPLANTATION, 2024, 108 (9S)
  • [6] Circulating neutrophil extracellular traps (NETs) in deceased donors prior to retrieval and during normothermic perfusion - An opportunity for donor liver optimisation in-situ, ex-situ and beyond.
    Abbas, Syed Hussain
    Dengu, Funga
    Sadik, Hatem
    Ceresa, Carlo
    Aswani, Andrew
    Friend, Peter
    TRANSPLANTATION, 2024, 108 (09) : 145 - 145
  • [7] Optimisation of donation after circulatory death livers - removal of extracellular histones during normothermic perfusion and following whole blood reperfusion in an ex-situ porcine model
    Abbas, Syed Hussain
    Dengu, Fungai
    Schofield, Jeremy
    Wang, Guozheng
    Morovat, Alireza
    Quaglia, Alberto
    Abrams, Simon T.
    Toh, Cheng-Hock
    Aswani, Andrew
    Friend, Peter
    TRANSPLANTATION, 2024, 108 (9S)
  • [8] Optimisation of donation after circulatory death livers removal of extracellular histones during normothermic perfusion and following whole blood reperfusion in an ex-situ porcine model
    Abbas, Syed Hussain
    Dengu, Fungai
    Schofield, Jeremy
    Wang, Guozheng
    Morovat, Alireza
    Quaglia, Alberto
    Abrams, Simon T.
    Toh, Cheng-Hock
    Aswani, Andrew
    Friend, Peter
    TRANSPLANTATION, 2024, 108 (09) : 456 - 456
  • [9] Ex situ reperfusion injury/inflammation: immuno-molecular profiling of human livers during normothermic machine perfusion
    Dengu, F.
    Critchley, W.
    Ceresa, C.
    Abbas, H.
    Lo Faro, M. L.
    Stone, J.
    Amin, K.
    Aswani, A.
    Micallef, J.
    Candiracci, J.
    Coussios, C.
    Ploeg, R.
    Nasralla, D.
    Fildes, J.
    Friend, P.
    TRANSPLANTATION, 2023, 107 (09) : 4 - 4
  • [10] The role of hypoxia inducible factor modulation and defatting in discarded steatotic human livers preserved with normothermic machine perfusion (NMP): observations from an ex-situ whole blood transplant model.
    Abbas, Syed Hussain
    Shaheed, Sadr
    Quaglia, Alberto
    Morovat, Alireza
    Dengu, Fungai
    Ebeling, Georg
    Sagar, Alex
    Ceresa, Carlo
    Hodson, Leanne
    Pugh, Christopher
    Friend, Peter
    TRANSPLANTATION, 2024, 108 (9S)
12