The autonomic nervous system in atrial fibrillation-pathophysiology and non-invasive assessment

被引:1
|
作者
Vandenberk, Bert [1 ,2 ]
Haemers, Peter [1 ,2 ]
Morillo, Carlos [3 ]
机构
[1] Univ Hosp Leuven, Dept Cardiol, Leuven, Belgium
[2] Katholieke Univ Leuven, Dept Cardiovasc Sci, Leuven, Belgium
[3] Univ Calgary, Libin Cardiovasc Inst, Cumming Sch Med, Dept Cardiac Sci, Calgary, AB, Canada
来源
关键词
atrial fibrillation; autonomic nervous system; pathophysiology; heart rate variability; heart rate turbulence; non-invasive assessment; HEART-RATE-VARIABILITY; MARSHALL ETHANOL INFUSION; PULMONARY VEIN ISOLATION; RATE TURBULENCE; BAROREFLEX SENSITIVITY; CATHETER ABLATION; RHYTHM ASSOCIATION; SPORT PRACTICE; INNERVATION; MECHANISMS;
D O I
10.3389/fcvm.2023.1327387
中图分类号
R5 [内科学];
学科分类号
1002 ; 100201 ;
摘要
The autonomic nervous system plays a crucial role in atrial fibrillation pathophysiology. Parasympathetic hyperactivity result in a shortening of the action potential duration, a reduction of the conduction wavelength, and as such facilitates reentry in the presence of triggers. Further, autonomic remodeling of atrial myocytes in AF includes progressive sympathetic hyperinnervation by increased atrial sympathetic nerve density and sympathetic atrial nerve sprouting. Knowledge on the pathophysiological process in AF, including the contribution of the autonomic nervous system, may in the near future guide personalized AF management. This review focuses on the role of the autonomic nervous system in atrial fibrillation pathophysiology and non-invasive assessment of the autonomic nervous system.
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页数:9
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