Pharmacological inhibition of ubiquitination sensitizes to DNA damaging agents by preventing homologous recombination repair

被引：0
|
作者：
Awasthi, Sharad
Yi, S. Stephen
McGrail, Daniel J.
Sahni, Nidhi
机构：
来源：
CANCER RESEARCH | 2023年 / 83卷 / 08期
关键词：
D O I：
10.1158/1538-7445.AM2023-LB043
中图分类号：
R73 [肿瘤学];
学科分类号：
100214 ;
摘要：
LB043
引用
收藏
页数：2
相关论文
共 50 条
  • [1] A CDC7 inhibitor sensitizes DNA-damaging chemotherapies by suppressing homologous recombination repair to delay DNA damage recovery
    Iwai, Kenichi
    Nambu, Tadahiro
    Kashima, Yukie
    Yu, Jie
    Eng, Kurt
    Miyamoto, Kazumasa
    Kakoi, Kazuyo
    Gotou, Masamitsu
    Takeuchi, Toshiyuki
    Kogame, Akifumi
    Sappal, Jessica
    Murai, Saomi
    Haeno, Hiroshi
    Kageyama, Shun-Ichiro
    Kurasawa, Osamu
    Niu, Huifeng
    Kannan, Karuppiah
    Ohashi, Akihiro
    SCIENCE ADVANCES, 2021, 7 (21)
  • [2] Induction of homologous recombination following in utero exposure to DNA-damaging agents
    Karia, Bijal
    Martinez, Jo Ann
    Bishop, Alexander J. R.
    DNA REPAIR, 2013, 12 (11) : 912 - 921
  • [3] Stellettin B Sensitizes Glioblastoma to DNA-Damaging Treatments by Suppressing PI3K-Mediated Homologous Recombination Repair
    Peng, Xin
    Zhang, Shaolu
    Wang, Yingying
    Zhou, Zhicheng
    Yu, Zixiang
    Zhong, Zhenxing
    Zhang, Liang
    Chen, Zhe-Sheng
    Claret, Francois X.
    Elkabets, Moshe
    Wang, Feng
    Sun, Fan
    Wang, Ran
    Liang, Han
    Lin, Hou-Wen
    Kong, Dexin
    ADVANCED SCIENCE, 2023, 10 (03)
  • [4] INHIBITION OF PARG, SENSITIZES OVARIAN CANCER CELLS TO PARP INHIBITORS AND DNA DAMAGING AGENTS
    Matanes, Emad
    Baloch, Tahira
    Octeau, David
    Kessous, Roy
    Kogan, Liron
    Laskov, Ido
    Gotlieb, Walter
    Yasmeen, Amber
    CLINICAL CANCER RESEARCH, 2019, 25 (22) : 228 - 228
  • [5] Inhibition of JNK Sensitizes Hypoxic Colon Cancer Cells to DNA-Damaging Agents
    Vasilevskaya, Irina A.
    Selvakumaran, Muthu
    Hierro, Lucia Cabal
    Goldstein, Sara R.
    Winkler, Jeffrey D.
    O'Dwyer, Peter J.
    CLINICAL CANCER RESEARCH, 2015, 21 (18) : 4143 - 4152
  • [6] Inhibition of PARG sensitizes ovarian cancer cells to PARP inhibitors and DNA damaging agents
    Matanes, E.
    Kogan, L.
    Lopez-Ozuna, V.
    Mitric, C.
    Raban, O.
    Eisenberg, N.
    Baloch, T.
    Salvador, S.
    Lau, S.
    Gotlieb, W. H.
    Yasmeen, A.
    GYNECOLOGIC ONCOLOGY, 2020, 159 : 137 - 137
  • [7] A rationally designed peptide enhances homologous recombination in vitro and resistance to DNA damaging agents in vivo
    Chen, Li-Tzu
    Wang, Andrew H. -J.
    NUCLEIC ACIDS RESEARCH, 2010, 38 (13) : 4361 - 4371
  • [8] DNA helicases in homologous recombination repair
    Branzei, Dana
    Szakal, Barnabas
    CURRENT OPINION IN GENETICS & DEVELOPMENT, 2021, 71 : 27 - 33
  • [9] Inhibition of JNK signaling sensitizes hypoxic colon cancer cells to DNA-damaging agents
    Vasilevskaya, Irina A.
    Selvakumaran, Muthu
    Cabal-Hierro, Lucia
    O'Dwyer, Peter J.
    CANCER RESEARCH, 2014, 74 (19)
  • [10] Gimeracil sensitizes cells to radiation via inhibition of homologous recombination
    Takagi, Masaru
    Sakata, Koh-ichi
    Someya, Masanori
    Tauchi, Hiroshi
    Iijima, Kenta
    Matsumoto, Yoshihisa
    Torigoe, Toshihiko
    Takahashi, Akari
    Hareyama, Masato
    Fukushima, Masakazu
    RADIOTHERAPY AND ONCOLOGY, 2010, 96 (02) : 259 - 266
12345