Organoids and Their Research Progress in Plastic and Reconstructive Surgery

被引：3

作者：

Wu, Huiting ^{[1
,2
]}

Wang, Guanhuier ^{[1
]}

Shang, Yujia ^{[1
,2
]}

Liu, Na ^{[1
,2
]}

Zhen, Yonghuan ^{[1
]}

Chen, Lixia ^{[2
]}

Li, Hua ^{[2
]}

An, Yang ^{[1
]}

机构：

[1] Peking Univ Third Hosp, Dept Plast Surg, 49 North Garden Rd, Beijing 100191, Peoples R China

[2] Shenyang Pharmaceut Univ, Sch Tradit Chinese Mat Med, Key Lab Struct Based Drug Design & Discovery, Dept Nat Prod Chem,Minist Educ, Shenyang 110016, Peoples R China

来源：

AESTHETIC PLASTIC SURGERY | 2023年 / 47卷 / 02期

关键词：

Organoids; Plastic surgery; Pluripotent stem cells; Bioscaffold; MESENCHYMAL STEM-CELLS; CARTILAGE LESIONS; BONE-MARROW; TISSUE; SKIN; HYDROGELS; REGENERATION; CULTURE; DIFFERENTIATION; DISEASE;

D O I：

10.1007/s00266-022-03129-6

中图分类号：

R61 [外科手术学];

学科分类号：

摘要：

Organoids are 3D structures generated from stem cells. Their functions and physiological characteristics are similar to those of normal organs. They are used in disease mechanism research, new drug development, organ transplantation and other fields. In recent years, the application of 3D materials in plastic surgery for repairing injuries, filling, tissue reconstruction and regeneration has also been investigated. The PubMed/MEDLINE database was queried to search for animal and human studies published through July of 2022 with search terms related to Organoids, Plastic Surgery, Pluripotent Stem Cells, Bioscaffold, Skin Reconstruction, Bone and Cartilage Regeneration. This review presents stem cells, scaffold materials and methods for the construction of organoids for plastic surgery, and it summarizes their research progress in plastic surgery in recent years.

引用

页码：880 / 891

页数：12

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