Transplacental transfer of Remdesivir and GS-441524: An ex vivo perfusion study

被引：0
|
作者：
Louchet, Margaux [1 ]
Ribot, Megane [1 ]
Bouazza, Naim [2 ]
Foissac, Frantz [2 ]
Froelicher, Leo [1 ]
Buth, Victoria [3 ]
Benaboud, Sihem [1 ]
Treluyer, Jean-Marc [1 ,2 ,3 ]
Lui, Gabrielle [1 ,3 ,4 ]
机构：
[1] Hop Cochin, Serv Pharmacol, Paris, France
[2] Hop Tarnier, AP HP, Unite Rech Clin, Paris, France
[3] CIC 1419 Mere Enfant Cochin Necker, Paris, France
[4] Hop Cochin, Serv Pharmacol, 27 Rue Faubourg St Jacques, F-75014 Paris, France
来源：
HEALTH SCIENCE REPORTS | 2023年 / 6卷 / 07期
关键词：
ex vivo cotyledon perfusion; GS-441524; placenta; Remdesivir; transplacental transfer; EXPRESSION; GENE;
D O I：
10.1002/hsr2.1144
中图分类号：
R1 [预防医学、卫生学];
学科分类号：
1004 ; 120402 ;
摘要：
引用
收藏
页数：4
相关论文
共 50 条
  • [1] Remdesivir and GS-441524
    Yan, Victoria
    CHEMICAL & ENGINEERING NEWS, 2021, 99 (23) : 3 - 3
  • [2] Remdesivir and GS-441524 Extraction by Ex Vivo Extracorporeal Life Support Circuits
    Imburgia, Carina E.
    Rower, Joseph E.
    Green, Danielle J.
    Mcknite, Autumn M.
    Kelley, Walter E.
    Reilly, Christopher A.
    Watt, Kevin M.
    ASAIO JOURNAL, 2022, 68 (09) : 1204 - 1210
  • [3] Practical and Highly Efficient Synthesis of Remdesivir from GS-441524
    Hu, Tianwen
    Zhu, Fuqiang
    Xiang, Li
    Shen, Jingshan
    Xie, Yuanchao
    Aisa, Haji A.
    ACS OMEGA, 2022, 7 (31): : 27516 - 27522
  • [4] NEW AND PRACTICAL SYNTHESIS OF GS-441524, THE KEY INTERMEDIATE OF REMDESIVIR
    Li, Bo
    Wang, Han
    Sun, Cong
    Lu, Sheng
    Kang, LinLin
    Jiang, Shun
    HETEROCYCLES, 2021, 102 (09) : 1797 - 1802
  • [5] Pharmacokinetics of Remdesivir and GS-441524 during PIRRT and Seraph 100 Therapy
    Schmidt, Julius J.
    Bode-Boeger, Stefanie M.
    Martens-Lobenhoffer, Jens
    Hoeper, Marius M.
    Kielstein, Jan T.
    CLINICAL JOURNAL OF THE AMERICAN SOCIETY OF NEPHROLOGY, 2021, 16 (08): : 1256 - 1257
  • [6] An efficient synthesis of RNA containing GS-441524: the nucleoside precursor of remdesivir
    Moorthy, Ramkumar
    Kennelly, Samantha A.
    Rodriguez, Deborah J.
    Harki, Daniel A.
    RSC ADVANCES, 2021, 11 (50) : 31373 - 31376
  • [7] Captisol and GS-704277, but Not GS-441524, Are Credible Mediators of Remdesivir's Nephrotoxicity
    Yan, Victoria C.
    Muller, Florian L.
    ANTIMICROBIAL AGENTS AND CHEMOTHERAPY, 2020, 64 (12)
  • [8] Can remdesivir and its parent nucleoside GS-441524 be potential oral drugs? An in vitro and in vivo DMPK assessment
    Xie, Jiashu
    Wang, Zhengqiang
    ACTA PHARMACEUTICA SINICA B, 2021, 11 (06) : 1607 - 1616
  • [9] Population Pharmacokinetics of Remdesivir and GS-441524 in Hospitalized COVID-19 Patients
    Leegwater, E.
    Moes, D. J. A. R.
    Bosma, L. B. E.
    Ottens, T. H.
    van der Meer, I. M.
    van Nieuwkoop, C.
    Wilms, E. B.
    ANTIMICROBIAL AGENTS AND CHEMOTHERAPY, 2022, 66 (06)
  • [10] Biotransformation and transplacental transfer of the anti-viral remdesivir and predominant metabolite, GS- 441524 in rats
    Yang, Ling
    Lin, I-Hsin
    Lin, Lie-Chwen
    Dalley, Jeffrey W.
    Tsai, Tung-Hu
    EBIOMEDICINE, 2022, 81
12345