The neurocircuitry of fasting-induced glucocorticoid release

被引：1
|
作者：
Jaschke, Nikolai P. [1 ,2 ]
Wang, Andrew [2 ]
机构：
[1] Tech Univ Dresden, Fac Med, Dept Med 3, Div Endocrinol, Dresden, Germany
[2] Yale Sch Med, Dept Immunobiol, New Haven, CT 06510 USA
来源：
CELL METABOLISM | 2023年 / 35卷 / 09期
关键词：
D O I：
10.1016/j.cmet.2023.08.004
中图分类号：
Q2 [细胞生物学];
学科分类号：
071009 ; 090102 ;
摘要：
Activation of the hypothalamus-pituitary-adrenal gland (HPA) axis confers adaptations to homeostatic perturbations including food scarcity. A comprehensive new study by Douglass et al. disentangled how agouti-related peptide (AgRP)-expressing neurons of the arcuate nucleus (ARC) trigger rapid HPA-axis activation in response to fasting, which is mediated by repression of a tonic, inhibitory neuro circuit.
引用
收藏
页码：1497 / 1499
页数：3
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