Base-controlled copper-catalyzed multi-component cascade reactions of cyanamides, diaryliodonium triflates and propargylamine for rapid assembly of polysubstituted 2-aminoimidazoles and 2-iminoimidazoles

被引：1

作者：

Yang, Run ^{[1
]}

Zhao, Yiming ^{[1
]}

Wang, Shihan ^{[1
]}

Wu, Canming ^{[2
]}

Li, Jihui ^{[1
,2
]}

Xu, Shuying ^{[1
]}

机构：

[1] Hainan Univ, Sch Chem Engn & Technol, Key Lab, Minist Educ Adv Mat Trop Isl Resources, Haikou 570228, Hainan, Peoples R China

[2] Hainan Univ, Sch Sci, Haikou 570228, Hainan, Peoples R China

来源：

NEW JOURNAL OF CHEMISTRY | 2023年 / 47卷 / 18期

基金：

海南省自然科学基金; 中国国家自然科学基金;

关键词：

SUBSTITUTED; 2-AMINOIMIDAZOLES; CARBON-DIOXIDE; ACCESS; SALTS; ALKALOIDS; CHEMISTRY; RECEPTOR; ALKYNES; AMINES; ROUTE;

D O I：

10.1039/d3nj01373a

中图分类号：

O6 [化学];

学科分类号：

0703 ;

摘要：

Copper-catalyzed three-component and four-component cascade reactions of cyanamides, dirayliodonium triflates, and propargylamine were established for the rapid construction of polysubstituted 2-aminoimidazoles and 2-iminoimidazoles using K2CO3 and pyridine as the base, respectively. Each reaction step was efficiently accelerated by copper, and 3-4 C-N bonds were constructed with excellent regioselectivities and good yields.

引用

页码：8494 / 8498

页数：5