Potential diagnostic value of miRNAs in sexually transmitted infections

被引：0

作者：

Peng, Yunchi ^{[1
]}

Xiao, Shuangwen ^{[1
]}

Zuo, Wei ^{[1
]}

Xie, Yafeng ^{[1
]}

Xiao, Yongjian ^{[1
]}

机构：

[1] Univ South China, Affiliated Hosp 2, Hengyang Med Sch, Dept Clin Lab, Hengyang 421001, Peoples R China

来源：

GENE | 2024年 / 895卷

关键词：

miRNA; STIs; Biomarker; Diagnosis; HSV; HPV; Chlamydia; HIV; HERPES-SIMPLEX-VIRUS; LATENCY-ASSOCIATED TRANSCRIPT; CERVICAL-CANCER; HSV-1; REPLICATION; PRODUCTIVE INFECTION; MICRORNAS; EXPRESSION; HOST; HEPATITIS; CHLAMYDIA;

D O I：

10.1016/j.gene.2023.147992

中图分类号：

Q3 [遗传学];

学科分类号：

071007 ; 090102 ;

摘要：

MiRNAs are small endogenous non-coding RNAs that have been demonstrated to be involved in posttranscriptional gene silencing, regulating a number of metabolic functions in the human body, including immune response, cellular physiology, organ development, angiogenesis, signaling, and other aspects. As popular molecules that have been studied in previous years, given their extensive regulatory functions, miRNAs hold considerable promise as non-invasive biomarkers. Sexually transmitted infections(STIs) are still widespread and have an adverse effect on individuals, communities, and society worldwide. miRNAs in the regulatory networks are generally involved in their molecular processes of formation and development. In this review, we discuss the value of miRNAs for the diagnosis of STIs.

引用

页数：13

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