European Society for Organ Transplantation (ESOT) Consensus Statement on the Role of Pancreas Machine Perfusion to Increase the Donor Pool for Beta Cell Replacement Therapy

被引：5

作者：

Ferrer-Fabrega, Joana ^{[1
,2
,3
,4
]}

Mesnard, Benoit ^{[5
,6
]}

Messner, Franka ^{[7
]}

Doppenberg, Jason B. ^{[8
]}

Drachenberg, Cinthia ^{[9
]}

Engelse, Marten A. ^{[8
]}

Johnson, Paul R. V. ^{[10
]}

Leuvenink, Henri G. D. ^{[11
]}

Oniscu, Gabriel C. ^{[12
]}

Papalois, Vassilios ^{[13
]}

Ploeg, Rutger J. ^{[14
]}

Reichman, Trevor W. ^{[15
]}

Scott III, William E. ^{[16
]}

Vistoli, Fabio ^{[17
]}

Berney, Thierry ^{[18
]}

Jacobs-Tulleneers-Thevissen, Daniel ^{[19
,20
]}

Kessaris, Nicos ^{[21
]}

Weissenbacher, Annemarie ^{[7
]}

Ogbemudia, Ann Etohan ^{[14
]}

White, Steve ^{[22
]}

Branchereau, Julien ^{[5
,6
]}

机构：

[1] Univ Barcelona, Hosp Clin, Inst Clin Digest & Metab Dis ICMDiM, Dept Surg,Hepatobiliopancreat Surg & Liver & Pancr, Barcelona, Spain

[2] Hosp Clin Barcelona, Barcelona Clin Liver Canc Grp BCLC, Hepat Oncol Unit, Barcelona, Spain

[3] Univ Barcelona, Res Inst IDIBAPS, August Pi i Sunyer Biomed, Barcelona, Spain

[4] CIBEREHD, Network Biomed Res Hepat & Digest Dis, Barcelona, Spain

[5] Nantes Univ Hosp, Dept Urol & Transplantat Surg, Nantes, France

[6] INSERM, Ctr Res Transplantat & Translat Immunol, ITUN5, UMR 1064, Nantes, France

[7] Med Univ Innsbruck, Dept Visceral Transplant & Thorac Surg, Innsbruck, Austria

[8] Leiden Univ, Transplantat Ctr, Med Ctr, Leiden, Netherlands

[9] Univ Maryland, Dept Pathol, Sch Med, Baltimore, MD USA

[10] Univ Oxford, John Radcliffe Hosp, Nuffield Dept Surg Sci, Res Grp Islet Transplantat, Oxford, England

[11] Univ Med Ctr Groningen, Dept Surg, Groningen, Netherlands

[12] Karolinska Inst, Dept Clin Sci Intervent & Technol, Transplant Div, CLINTEC, Stockholm, Sweden

[13] Imperial Coll Healthcare NHS Trust, Hammersmith Hosp, Imperial Coll Renal & Transplant Ctr, London, England

[14] Univ Oxford, Oxford Transplant Ctr, Nuffield Dept Surg Sci, Oxford, England

[15] Univ Hlth Network, Toronto Gen Hosp, Ajmera Transplant Ctr, Toronto, ON, Canada

[16] Newcastle Univ, Translat & Clin Res Inst, Newcastle Upon Tyne, England

[17] Univ Pisa, Div Gen Surg & Transplantat, Pisa, Italy

[18] Univ Geneva Hosp, Dept Surg, Div Transplantat, Geneva, Switzerland

[19] Vrije Univ Brussel, Diabet Res Ctr, Brussels, Belgium

[20] Vrije Univ Brussel, Univ Ziekenhuis Brussel, Dept Surg, Brussels, Belgium

[21] Guys Hosp, Dept Nephrol & Transplantat, London, England

[22] Univ Newcastle Tyne, Freeman Hosp, Dept HPB & Transplant Surg, NIHR BTRU Organ Donat & Transplantat, Newcastle Upon Tyne, England

来源：

TRANSPLANT INTERNATIONAL | 2023年 / 36卷

关键词：

islet transplantation; ischemia-reperfusion injury; machine perfusion; persufflation; whole pancreas transplantation; WHOLE PANCREAS; PRESERVATION; ISLET;

D O I：

10.3389/ti.2023.11374

中图分类号：

R61 [外科手术学];

学科分类号：

摘要：

The advent of Machine Perfusion (MP) as a superior form of preservation and assessment for cold storage of both high-risk kidney's and the liver presents opportunities in the field of beta-cell replacement. It is yet unknown whether such techniques, when applied to the pancreas, can increase the pool of suitable donor organs as well as ameliorating the effects of ischemia incurred during the retrieval process. Recent experimental models of pancreatic MP appear promising. Applications of MP to the pancreas, needs refinement regarding perfusion protocols and organ viability assessment criteria. To address the "Role of pancreas machine perfusion to increase the donor pool for beta cell replacement," the European Society for Organ Transplantation (ESOT) assembled a dedicated working group comprising of experts to review literature pertaining to the role of MP as a method of improving donor pancreas quality as well as quantity available for transplant, and to develop guidelines founded on evidence-based reviews in experimental and clinical settings. These were subsequently refined during the Consensus Conference when this took place in Prague.

引用

页数：11

共 8 条

[1] European Society of Organ Transplantation (ESOT) Consensus Statement on Machine Perfusion in Cardiothoracic Transplant
Amarelli, Cristiano
Bello, Irene
Aigner, Clemens
Berman, Marius
Boffini, Massimo
Clark, Stephen
Dalvindt, Marita
de Wolf, Julien
Ensminger, Stephan
de Antonio, David Gomez
Hoyos, Lucas
Palmieri, Lucrezia
Schweiger, Martin
Sponga, Sandro
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TRANSPLANT INTERNATIONAL, 2024, 37
[2] European Society of Organ Transplantation (ESOT) Consensus Statement on Prehabilitation for Solid Organ Transplantation Candidates
Annema, Coby
De Smet, Stefan
Castle, Ellen M.
Overloop, Yasna
Klaase, Joost M.
Janaudis-Ferreira, Tania
Mathur, Sunita
Kouidi, Evangelia
Perez Saez, Maria Jose
Matthys, Christophe
Dobbels, Fabienne
Ferrari, Pisana
Golebiewska, Justyna
Mrzljak, Anna
Girman, Peter
Perch, Michael
Lopez-Lopez, Victor
White, Colin
Koval, Dmytro
Greenwood, Sharlene
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TRANSPLANT INTERNATIONAL, 2023, 36
[3] European Society for Organ Transplantation (ESOT) Consensus Statement on Outcome Measures in Liver Transplantation According to Value-Based Health Care
Carbone, Marco
Neuberger, James
Rowe, Ian
Polak, Wojciech G.
Forsberg, Anna
Fondevila, Constantino
Mantovani, Lorenzo
Nardi, Alessandra
Colli, Agostino
Rockell, Karen
Schick, Liz
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[4] European Society for Organ Transplantation (ESOT) Consensus Statement on the Use of Non-invasive Biomarkers for Cardiothoracic Transplant Rejection Surveillance
Nikolova, Andriana
Agbor-Enoh, Sean
Bos, Saskia
Crespo-Leiro, Marisa
Ensminger, Stephan
Jimenez-Blanco, Marta
Minervini, Annamaria
Perch, Michael
Segovia, Javier
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TRANSPLANT INTERNATIONAL, 2024, 37
[5] Liver Transplantation for Primary Sclerosing Cholangitis (PSC) With or Without Inflammatory Bowel Disease (IBD)-A European Society of Organ Transplantation (ESOT) Consensus Statement
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TRANSPLANT INTERNATIONAL, 2023, 36
[6] European Society for Organ Transplantation (ESOT)-TLJ 3.0 Consensus on Histopathological Analysis of Pre-Implantation Donor Kidney Biopsy: Redefining the Role in the Process of Graft Assessment
Zaza, Gianluigi
Cucchiari, David
Becker, Jan Ulrich
de Vries, Aiko P. J.
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[7] European Society for Organ Transplantation(ESOT)- TLJ 3.0 Consensus on Histopathological Analysis of Pre-Implantation Donor Kidney Biopsy: Redefining the Role in the Process of Graft Assessment
Zaza, G.
Cucchiari, D.
Becker, J. U.
de Vries, A. P.
Eccher, A.
Florquin, S.
Kers, J.
Marson, L.
Pengel, L.
Rabant, M.
Rossini, M.
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AMERICAN JOURNAL OF TRANSPLANTATION, 2023, 23 (06) : S826 - S826
[8] Consensus statement on normothermic regional perfusion in donation after circulatory death: Report from the European Society for Organ Transplantation's Transplant Learning Journey
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Hessheimer, Amelia J.
Neyrinck, Arne P.
Paredes, David
Bellini, Maria Irene
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TRANSPLANT INTERNATIONAL, 2021, 34 (11) : 2019 - 2030

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