Choices and Challenges With Treatment of Myasthenia Gravis in Pregnancy: A Systematic Review

被引:2
|
作者
Kumar, Lakshya [1 ]
Kachhadia, Meet Popatbhai [1 ]
Kaur, Jashanpreet [2 ]
Patel, Harshkumar [1 ]
Noor, Khutaija [3 ]
Gohel, Rushi G. [1 ]
Kaur, Paramjeet [4 ]
Raiyani, Siddharth [1 ]
Gohel, Vatsal A. [5 ]
Vasavada, Advait M. [6 ,7 ]
机构
[1] Pandit Dindayal Upadhyay PDU Med Coll, Internal Med, Rajkot, India
[2] Mata Gujri Mem Med Coll, Internal Med, Kishanganj, India
[3] Shadan Inst Med Sci, Internal Med, Hyderabad, Pakistan
[4] Guru Gobind Singh Med Coll, Internal Med, Faridkot, India
[5] Karaganda Med Univ, Internal Med, Karaganda, Kazakhstan
[6] M P Shah Med Coll, Internal Med, Jamnagar, India
[7] Calif Inst Behav Neurosci & Psychol, Internal Med, Fairfield, CT USA
关键词
during pregnancy; pregnancy counseling; pregnancy; highrisk pregnancy; neuromuscular junction; disorders; myasthenia gravis (mg) in pregnancy; myasthenia gravis (mg); INCREASED RISK; MANAGEMENT; GUIDELINES; DELIVERY; OUTCOMES; MOTHERS; UPDATE; SERIES; ONSET; WOMEN;
D O I
10.7759/cureus.42772
中图分类号
R5 [内科学];
学科分类号
1002 ; 100201 ;
摘要
Myasthenia gravis (MG) is an autoimmune disease affecting young women in their second and third decades, coinciding with their reproductive years. We aim to explore the choices and challenges in the treatment of MG in pregnancy. Cochrane, PubMed, Google Scholar, and Embase were the four databases systematically searched for studies with patients reporting pregnancy outcomes for women with MG during pregnancy using the Preferred Reporting Items for Systematic Reviews and Meta-Analysis (PRISMA) technique. Quality assessment was done using the Joanna Briggs Institute critical tool (JBI, Adelaide, Australia) for methodological quality. From 2000 to 2023, 40 studies from database search results were considered. There is a substantial risk of complications with MG, especially if it appears during pregnancy. In particular, widespread weakness is a cause of severe, life-threatening disorders, but several treatment options are available.
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页数:15
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