Scant research has utilized person-centred approaches to investigate associations between patterns of drinking motive facets and alcohol-related outcomes and depressive symptoms. To address this gap, 1,216 first- and second-year Chinese college students (Mean age = 19.14, SD = 0.94, 37.3% male) who had consumed alcohol in the past year were surveyed by questionnaires. Latent profile analysis was used to identify distinct classes based on four drinking motives: enhancement, coping, conformity, and social motives. A 5-profile solution provided the best overall model fit to the data, including the 'low' (n = 712; 58.6%), 'moderate' (n = 213; 17.5%), 'high' (n = 120; 9.9%), 'high external/low internal reinforcing' (n = 108; 8.9%), and 'high positive/low negative reinforcing' motives groups (n = 63; 5.2%). Students with high drinking motives endorsed the highest levels of alcohol use outcomes and depression symptoms, while reporting the lowest level of drinking refusal self-efficacy. Students with moderate motives tended to occupy the middle position across all outcome variables. Students characterized by high external/low internal motives reported elevated depressive symptoms and drinking-related problems. Those with high positive/low negative motives exhibited high drinking intention and alcohol consumption, but low levels of drinking-related problems and depressive symptoms. These findings shed light on the heterogeneity among college student drinkers, paving the way for targeted alcohol interventions tailored to diverse drinking motive patterns.