An All-Dielectric Metamaterial Terahertz Biosensor for Cytokine Detection

被引：1
|
作者：
Men, Kuo [1 ,2 ,3 ,4 ]
Lian, Ziwei [1 ,2 ,3 ,4 ]
Tu, Hailing [1 ]
Zhao, Hongbin [1 ]
Wei, Qianhui [1 ,2 ,3 ]
Jin, Qingxi [1 ,2 ,4 ]
Mao, Changhui [1 ]
Wei, Feng [1 ,3 ]
机构：
[1] GRINM Grp Co Ltd, State Key Lab Adv Mat Smart Sensing, Beijing 100088, Peoples R China
[2] GRIMAT Engn Inst Co Ltd, Beijing 101402, Peoples R China
[3] GRINM Guangdong Inst Adv Mat & Technol, Foshan 528051, Peoples R China
[4] Gen Res Inst Nonferrous Met, Beijing 100088, Peoples R China
来源：
MICROMACHINES | 2024年 / 15卷 / 01期
关键词：
all-dielectric metamaterial; terahertz biosensor; cytokine; FANO RESONANCE;
D O I：
10.3390/mi15010053
中图分类号：
O65 [分析化学];
学科分类号：
070302 ; 081704 ;
摘要：
In this paper, we report an all-dielectric metamaterial terahertz biosensor, which exhibits a high Q factor of 35 at an 0.82 resonance peak. A structure with an electromagnetically induced transparency effect was designed and fabricated to perform a Mie resonance for the terahertz response. The biosensor exhibits a limit of detection of 100 pg/mL for cytokine interleukin 2 (IL-2) and a linear response for the logarithm of the concentration of IL-2 in the range of 100 pg/mL to 1 mu g/mL. This study implicates an important potential for the detection of cytokines in serum and has potential application in the clinical detection of cytokine release syndrome.
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页数：9
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