ENPP1-Fc expressing AAV vector prevents ectopic tissue calcification and restores bone parameters in ENPP1 deficient mice

被引：0

作者：

O'Brien, Kevin ^{[1
]}

Flaman, Lisa ^{[1
]}

Sullivan, Caitlin ^{[1
]}

Howe, Jennifer ^{[1
]}

Lynch, Angela ^{[1
]}

Schrier, Denis ^{[1
]}

Cheng, Zhiliang ^{[1
]}

Jungles, Steve ^{[1
]}

Sabbagh, Yves ^{[1
]}

机构：

[1] Inozyme Pharma, Boston, MA USA

来源：

JOURNAL OF BONE AND MINERAL RESEARCH | 2023年 / 38卷

关键词：

D O I：

暂无

中图分类号：

R5 [内科学];

学科分类号：

1002 ; 100201 ;

摘要：

LB SUN-904

引用

页码：341 / 341

页数：1

共 28 条

[1] Treatment with an AAV vector expressing ENPP1-Fc prevents ectopic tissue calcification and restores bone parameters in ENPP1 deficient mice
O'Brien, Kevin
Sullivan, Caitlin
Howe, Jennifer
Jungles, Steven
Lynch, Angela
Schrier, Denis
Sabbagh, Yves
Cheng, Zhiliang
JOURNAL OF BONE AND MINERAL RESEARCH, 2022, 37 : 197 - 197
[2] INZ-701 prevents ectopic tissue calcification and restores growth in ENPP1 deficient mice
Cheng, Zhiliang
O'Brien, Kevin
Sullivan, Caitlin
Howe, Jennifer
Schrier, Denis
Thompson, David
Jungles, Steve
JOURNAL OF BONE AND MINERAL RESEARCH, 2020, 35 : 42 - 42
[3] INZ-701, a recombinant ENPP1-Fc protein, effectively treats and prevents neointimal proliferation in WT and ENPP1 Deficient mice
Rutsch, F.
O'brien, K.
Nitschke, Y.
Sullivan, C.
Howe, J.
Lynch, A.
Schrier, D.
Thompson, D.
Sabbagh, Y.
CARDIOVASCULAR RESEARCH, 2022, 118 (SUPPL 1)
[4] INZ-701 Prevents Ectopic Tissue Calcification and Restores Bone Architecture and Growth in ENPP1-Deficient Mice
Cheng, Zhiliang
O'Brien, Kevin
Howe, Jennifer
Sullivan, Caitlin
Schrier, Denis
Lynch, Angela
Jungles, Steven
Sabbagh, Yves
Thompson, David
JOURNAL OF BONE AND MINERAL RESEARCH, 2021, 36 (08) : 1594 - 1604
[5] Bone-targeted ENPP1-Fc suppresses spinal hyperostosis and prevents hearing loss and spinal osteoporosis in murine ENPP1 deficiency
Srivastava, Shivani
Stabach, Paul
Weise, Keith
Von Kroge, Simon
Oheim, Ralf
Carpenter, Thomas
Tommasini, Steven
Braddock, Demetrios
JOURNAL OF BONE AND MINERAL RESEARCH, 2023, 38 : 77 - 77
[6] ENPP1 in Blood and Bone: Skeletal and Soft Tissue Diseases Induced by ENPP1 Deficiency
Ferreira, Carlos R.
Carpenter, Thomas O.
Braddock, Demetrios T.
ANNUAL REVIEW OF PATHOLOGY-MECHANISMS OF DISEASE, 2024, 19 : 507 - 540
[7] ENPP1-Fc prevents mortality and vascular calcifications in rodent model of generalized arterial calcification of infancy
Albright, Ronald A.
Stabach, Paul
Cao, Wenxiang
Kavanagh, Dillon
Mullen, Isabelle
Braddock, Alexander A.
Covo, Mariel S.
Tehan, Martin
Yang, Guangxiao
Cheng, Zhiliang
Bouchard, Keith
Yu, Zhao-Xue
Thorn, Stephanie
Wang, Xiangning
Folta-Stogniew, Ewa J.
Negrete, Alejandro
Sinusas, Albert J.
Shiloach, Joseph
Zubal, George
Madri, Joseph A.
De La Cruz, Enrique M.
Braddock, Demetrios T.
NATURE COMMUNICATIONS, 2015, 6
[8] ENPP1-Fc prevents mortality and vascular calcifications in rodent model of generalized arterial calcification of infancy
Ronald A. Albright
Paul Stabach
Wenxiang Cao
Dillon Kavanagh
Isabelle Mullen
Alexander A. Braddock
Mariel S. Covo
Martin Tehan
Guangxiao Yang
Zhiliang Cheng
Keith Bouchard
Zhao-Xue Yu
Stephanie Thorn
Xiangning Wang
Ewa J. Folta-Stogniew
Alejandro Negrete
Albert J. Sinusas
Joseph Shiloach
George Zubal
Joseph A. Madri
Enrique M. De La Cruz
Demetrios T. Braddock
Nature Communications, 6
[9] ENPP1-Fc prevents neointima formation in generalized arterial calcification of infancy through the generation of AMP
Yvonne Nitschke
Yan Yan
Insa Buers
Kristina Kintziger
Kim Askew
Frank Rutsch
Experimental & Molecular Medicine, 2018, 50 : 1 - 12
[10] ENPP1-Fc prevents neointima formation in generalized arterial calcification of infancy through the generation of AMP
Nitschke, Yvonne
Yan, Yan
Buers, Insa
Kintziger, Kristina
Askew, Kim
Rutsch, Frank
EXPERIMENTAL AND MOLECULAR MEDICINE, 2018, 50 : 1 - 12

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