Optimizing the Threshold to Treat Children for Latent Tuberculosis Infection: A North-East England Experience
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作者:
Porter, George James
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机构:
Newcastle Univ, Populat Hlth Sci Inst, Newcastle Upon Tyne, England
Newcastle Upon Tyne NHS Fdn Trust, Great North Childrens Hosp, Newcastle Upon Tyne, England
Newcastle Univ, Populat Hlth Sci Inst, Newcastle Upon Tyne NE1 7RU, EnglandNewcastle Univ, Populat Hlth Sci Inst, Newcastle Upon Tyne, England
Porter, George James
[1
,2
,5
]
Whyte, Martin
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机构:
James Cook Univ Hosp, Dept Paediat, Middlesbrough, EnglandNewcastle Univ, Populat Hlth Sci Inst, Newcastle Upon Tyne, England
Whyte, Martin
[3
]
Walters, Elisabetta Ghimenton
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机构:
Newcastle Upon Tyne NHS Fdn Trust, Great North Childrens Hosp, Newcastle Upon Tyne, England
Stellenbosch Univ, Desmond Tutu TB Ctr, Cape Town, South AfricaNewcastle Univ, Populat Hlth Sci Inst, Newcastle Upon Tyne, England
Walters, Elisabetta Ghimenton
[2
,4
]
Owens, Stephen
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机构:
Newcastle Univ, Populat Hlth Sci Inst, Newcastle Upon Tyne, England
Newcastle Upon Tyne NHS Fdn Trust, Great North Childrens Hosp, Newcastle Upon Tyne, EnglandNewcastle Univ, Populat Hlth Sci Inst, Newcastle Upon Tyne, England
Owens, Stephen
[1
,2
]
机构:
[1] Newcastle Univ, Populat Hlth Sci Inst, Newcastle Upon Tyne, England
[2] Newcastle Upon Tyne NHS Fdn Trust, Great North Childrens Hosp, Newcastle Upon Tyne, England
[3] James Cook Univ Hosp, Dept Paediat, Middlesbrough, England
[4] Stellenbosch Univ, Desmond Tutu TB Ctr, Cape Town, South Africa
[5] Newcastle Univ, Populat Hlth Sci Inst, Newcastle Upon Tyne NE1 7RU, England
latent tuberculosis;
mass screening;
tuberculin test;
pediatrics;
D O I:
10.1097/INF.0000000000003786
中图分类号:
R392 [医学免疫学];
Q939.91 [免疫学];
学科分类号:
100102 ;
摘要:
We assessed the impact of the updated guidelines on tuberculin skin test interpretation in the North East of England. Data on 241 children screened for latent tuberculosis infection (LTBI) between January 2011 and July 2018 were analyzed; 12.4% of children screened under the previous guidelines were treated for LTBI, compared to 33.3% under the new ones (P < 0.001).