Evaluation of Antibacterial and Antiviral Compounds from Commiphora myrrha (T.Nees) Engl. Resin and Their Promising Application with Biochar

被引:0
|
作者
Kim, Jin Woo [1 ,2 ]
Park, Saerom [1 ,3 ]
Sung, Young Whan [1 ]
Song, Hak Jin [1 ]
Yang, Sung Woo [1 ]
Han, Jiwoo [1 ]
Jo, Jeong Wook [1 ]
Lee, Im-Soon [4 ]
Lee, Sang Hyun [1 ]
Choi, Yong-Keun [1 ,3 ]
Kim, Hyung Joo [1 ]
机构
[1] Konkuk Univ, Dept Biol Engn, Seoul 05029, South Korea
[2] Myrrhzone Molyac Inst Co Ltd, R&D Ctr, Chungcheongbuk Do 27856, South Korea
[3] Choilab Inc, R&D Ctr, Seoul 01811, South Korea
[4] Konkuk Univ, Dept Biol Sci, Seoul 05029, South Korea
来源
APPLIED SCIENCES-BASEL | 2023年 / 13卷 / 18期
关键词
C. myrrha (T.Nees) Engl; antivirus; furanoeudesma-1,3-diene; curzerene; biochar; PHENOLIC-COMPOUNDS; NATURAL-PRODUCTS; GENOME SEQUENCE; SP-NOV; EXTRACTION; ANTIOXIDANT; IDENTIFICATION;
D O I
10.3390/app131810549
中图分类号
O6 [化学];
学科分类号
0703 ;
摘要
Commiphora myrrha (T.Nees) Engl. resin extracts were prepared via immersion in extraction solvents (hot water, DMSO, hexane, ethanol, and methanol) which have various physical properties, such as different polarity and dielectric constant values. Methanolic C. myrrha (T.Nees) Engl. resin extracts showed broad antibacterial activity against isolated airborne bacteria. All methanolic C. myrrha (T.Nees) Engl. resin extracts were analyzed using GC-MS and Furanoeudesma-1,3-diene and curzerene were found as the main terpenoids. In addition, the methanolic C. myrrha (T.Nees) Engl. resin extracts were found to have antiviral activity (81.2% viral RNA inhibition) against the H1N1 influenza virus. Biochars (wood powder- and rice husk-derived) coated with C. myrrha (T.Nees) Engl. resin extracts also showed antiviral activity (22.6% and 24.3% viral RNA inhibition) due to the adsorption of terpenoids onto biochar. C. myrrha (T.Nees) Engl. resin extract using methanol as the extraction solvent is a promising agent with antibacterial and antiviral efficacy that can be utilized as a novel material via adsorption onto biochar for air filtration processes, cosmetics, fertilizers, drug delivery, and corrosion inhibition.
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页数:17
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