Gut microbiome is not associated with mild cognitive impairment in Parkinson's disease

被引：0

作者：

Aho, Velma T. E. ^{[1
]}

Klee, Matthias ^{[2
]}

Landoulsi, Zied ^{[1
]}

Heintz-Buschart, Anna ^{[3
]}

Pavelka, Lukas ^{[1
,4
,5
]}

Leist, Anja K. ^{[2
]}

Krueger, Rejko ^{[1
,4
,5
,6
]}

May, Patrick ^{[1
]}

Wilmes, Paul ^{[1
,7
]}

机构：

[1] Univ Luxembourg, Luxembourg Ctr Syst Biomed, Esch Sur Alzette, Luxembourg

[2] Univ Luxembourg, Inst Res Socioecon Inequal IRSEI, Dept Social Sci, Esch Sur Alzette, Luxembourg

[3] Univ Amsterdam, Swammerdam Inst Life Sci, Amsterdam, Netherlands

[4] Ctr Hosp Luxembourg, Parkinsons Res Clin, Luxembourg, Luxembourg

[5] Luxembourg Inst Hlth, Transversal Translat Med, Strassen, Luxembourg

[6] Ctr Hosp Luxembourg, Dept Neurol, Luxembourg, Luxembourg

[7] Univ Luxembourg, Fac Sci Technol & Med, Dept Life Sci & Med, Esch Sur Alzette, Luxembourg

来源：

NPJ PARKINSONS DISEASE | 2024年 / 10卷 / 01期

基金：

欧洲研究理事会;

关键词：

D O I：

10.1038/s41531-024-00687-1

中图分类号：

Q189 [神经科学];

学科分类号：

071006 ;

摘要：

Gut microbiome differences between people with Parkinson's disease (PD) and control subjects without Parkinsonism are widely reported, but potential alterations related to PD with mild cognitive impairment (MCI) have yet to be comprehensively explored. We compared gut microbial features of PD with MCI (n = 58) to cognitively unimpaired PD (n = 60) and control subjects (n = 90) with normal cognition. Our results did not support a specific microbiome signature related to MCI in PD.

引用

页数：6

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