Secukinumab in moderate to severe hidradenitis suppurativa: Week 16 results of hurley stage II and III from the sunshine and sunrise phase 3 randomized trials

被引:0
|
作者
Kimball, Alexa B. [1 ,2 ]
Alavi, Afsaneh [3 ,4 ]
Jemec, Gregor B. E. [3 ,5 ]
Zouboulis, Christos C. [3 ,6 ,7 ,8 ,9 ,10 ]
Wozniak, Magdalena B. [11 ]
Uhlmann, Lorenz [12 ]
Llobet-Martinez, Angela [12 ]
Ravichandran, Shoba [13 ]
Marzano, Angelo V. [3 ,14 ,15 ]
Reguiai, Ziad [3 ,16 ]
机构
[1] Harvard Med Sch, Boston, MA USA
[2] Beth Israel Deaconess Med Ctr, Dermatol, Boston, MA USA
[3] European Hidradenitis Suppurat Fdn eV, Dessau, Germany
[4] Mayo Clin, Dermatol, Rochester, MN USA
[5] Zealand Univ Hosp Roskilde, Dermatol, Roskilde, Denmark
[6] Brandenburg Med Sch Theodor Fontane, Dessau, Germany
[7] Staedt Klinikum Dessau, Fac Hlth Sci Brandenburg, Dept Dermatol, Dessau, Germany
[8] Staedt Klinikum Dessau, Fac Hlth Sci Brandenburg, Dept Venereol, Dessau, Germany
[9] Staedt Klinikum Dessau, Fac Hlth Sci Brandenburg, Dept Allergol, Dessau, Germany
[10] Staedt Klinikum Dessau, Fac Hlth Sci Brandenburg, Dept Immunol, Dessau, Germany
[11] Novartis Ireland Ltd, Dublin, Ireland
[12] Novartis Pharma AG, Basel, Switzerland
[13] Novartis Pharmaceut, E Hanover, NJ USA
[14] Fdn IRCCS Ca Granda Osped Maggiore Policlin, Milan, Italy
[15] Univ Milan, Dermatol Pathophysiol & Transplantat, Milan, Italy
[16] Polyclin Courlancy Bezannes, Dermatol, Reims, France
关键词
D O I
暂无
中图分类号
R75 [皮肤病学与性病学];
学科分类号
100206 ;
摘要
引用
收藏
页码:25 / 26
页数:2
相关论文
共 50 条
  • [1] Secukinumab in moderate to severe hidradenitis suppurativa: Analysis of pooled data from the SUNSHINE and SUNRISE phase 3 randomized trials
    Alavi, Afsaneh
    Reguiai, Ziad
    Jemec, Gregor B. E.
    Gottlieb, Alice B.
    Wozniak, Magdalena B.
    Uhlmann, Lorenz
    Fan, Heng
    Llobet-Martinez, Angela
    Ravichandran, Shoba
    Kimball, Alexa B.
    EXPERIMENTAL DERMATOLOGY, 2023, 32 : 137 - 138
  • [2] Secukinumab and concomitant antibiotic use in patients with moderate-to-severe hidradenitis suppurativa: Week 16 efficacy and safety results from the Phase 3 SUNSHINE and SUNRISE trials
    Kokolakis, Georgios
    Martorell, Antonio
    Kerdel, Francisco
    Bettoli, Vincenzo
    Giamarellos-Bourboulis, Evangelos J.
    Sinclair, Rodney
    Kasparek, Torben
    Li, Xianjun
    Martinez, Angela Llobet
    Uhlmann, Lorenz
    Muscianisi, Elisa
    JOURNAL OF THE AMERICAN ACADEMY OF DERMATOLOGY, 2023, 89 (03) : AB85 - AB85
  • [3] Secukinumab in moderate to severe hidradenitis suppurativa: Primary endpoint analysis from the SUNSHINE and SUNRISE Phase 3 trials
    Gottlieb, Alice B.
    Kimball, Alexa B.
    Alavi, Afsaneh
    Jemec, Gregor B. E.
    Wei, Xiaoling
    Wozniak, Magdalena B.
    Uhlmann, Lorenz
    Martinez, Angela Llobet
    Keefe, Deborah
    Martin, Ruvie
    Chen, Li
    Muscianisi, Elisa
    AUSTRALASIAN JOURNAL OF DERMATOLOGY, 2023, 64 : 25 - 26
  • [4] Efficacy of secukinumab in patients with moderate-to-severe hidradenitis suppurativa previously treated with biologic therapy: Week 16 results from the SUNSHINE and SUNRISE trials
    Zouboulis, Christos C.
    Passeron, Thierry
    Bastos, Pedro Mendes
    Pariser, David
    Offidani, Annamaria
    Kasparek, Torben
    Wozniak, Magdalena
    Li, Xianjun
    Uhlmann, Lorenz
    Muscianisi, Elisa
    JOURNAL OF THE AMERICAN ACADEMY OF DERMATOLOGY, 2023, 89 (03) : AB160 - AB160
  • [5] Efficacy and safety of secukinumab in patients with moderate-to-severe hidradenitis suppurativa: Final results from the Phase 3 SUNSHINE and SUNRISE trials
    Kimball, Alexa B.
    Jemec, Gregor B. E.
    Alavi, Afsaneh
    Reguiai, Ziad
    Gottlieb, Alice
    Wozniak, Magdalena B.
    Uhlmann, Lorenz
    Martinez, Angela Llobet
    Field, Claire
    Ravichandran, Shoba
    Muscianisi, Elisa
    JOURNAL OF THE AMERICAN ACADEMY OF DERMATOLOGY, 2023, 89 (03) : AB156 - AB156
  • [6] Effect of secukinumab on draining tunnels in patients with moderate to severe hidradenitis suppurativa: Post hoc analysis of the SUNSHINE and SUNRISE phase 3 randomized trials
    Bechara, Falk G.
    Becherel, Pierre-Andre
    Reguiai, Ziad
    Mendes-Bastos, Pedro
    Kirby, Joslyn S.
    Hsiao, Jennifer
    Bachhuber, Teresa
    Wozniak, Magdalena B.
    Kasparek, Torben
    Ortmann, Christine-Elke
    Lobach, Iryna
    Field, Clarice
    Ravichandran, Shoba
    Kimball, Alexa B.
    EXPERIMENTAL DERMATOLOGY, 2023, 32 : 140 - 141
  • [7] Secukinumab in moderate-to-severe hidradenitis suppurativa (SUNSHINE and SUNRISE): week 16 and week 52 results of two identical, multicentre, randomised, placebo-controlled, double-blind phase 3 trials
    Kimball, Alexa B.
    Jemec, Gregor B. E.
    Alavi, Afsaneh
    Reguiai, Ziad
    Gottlieb, Alice B.
    Bechara, Falk G.
    Paul, Carle
    Bourboulis, Evangelos J. Giamarellos
    Villani, Axel P.
    Schwinn, Andreas
    Rueff, Franziska
    Ramaya, Larisha Pillay
    Reich, Adam
    Lobo, Ines
    Sinclair, Rodney
    Passeron, Thierry
    Martorell, Antonio
    Mendes-Bastos, Pedro
    Kokolakis, Georgios
    Becherel, Pierre-Andre
    Wozniak, Magdalena B.
    Martinez, Angela Llobet
    Wei, Xiaoling
    Uhlmann, Lorenz
    Passera, Anna
    Keefe, Deborah
    Martin, Ruvie
    Field, Clarice
    Chen, Li
    Vandemeulebroecke, Marc
    Ravichandran, Shoba
    Muscianisi, Elisa
    LANCET, 2023, 401 (10378): : 747 - 761
  • [8] Secukinumab in patients with moderate-to-severe hidradenitis suppurativa based on prior biologic exposure: an efficacy and safety analysis from the SUNSHINE and SUNRISE phase III trials
    Zouboulis, Christos C.
    Passeron, Thierry
    Pariser, David
    Wozniak, Magdalena B.
    Li, Xianjun
    Uhlmann, Lorenz
    Lobach, Iryna
    Martinez, Angela Llobet
    Ravichandran, Shoba
    Alarcon, Ivette
    Offidani, Annamaria
    Alam, Maryam S.
    Mendes-Bastos, Pedro
    BRITISH JOURNAL OF DERMATOLOGY, 2024, 190 (06) : 836 - 845
  • [9] Impact of secukinumab on the need for rescue surgical intervention in patients with moderate to severe hidradenitis suppurativa: Post-hoc analysis of week 16 data from sunshine and sunrise trials
    van der Zee, Hessel H.
    Szepietowski, Jacek C.
    Sayed, Christopher
    Guillem, Philippe
    Hamzavi, Iltefat H.
    Goldberg, Stephanie
    Field, Clarice
    Ortmann, Christine-Elke
    Lobach, Iryna
    Wozniak, Magdalena B.
    Llobet-Martinez, Angela
    Ravichandran, Shoba
    Bachhuber, Teresa
    Bechara, Falk G.
    EXPERIMENTAL DERMATOLOGY, 2023, 32 : 30 - 31
  • [10] Long-term efficacy and safety of secukinumab in patients with moderate-to-severe hidradenitis suppurativa: week 104 results from the SUNSHINE and SUNRISE extension trial
    Kimball, Alexa B.
    Bechara, Falk G.
    Badat, Aysha
    Giamarellos-Bourboulis, Evangelos J.
    Gottlieb, Alice B.
    Jemec, Gregor B. E.
    Reguiai, Ziad
    Villani, Axel P.
    Alarcon, Ivette
    Bansal, Amita
    Gasperoni, Francesca
    Martin, Ruvie
    Paguet, Bertrand
    Uhlmann, Lorenz
    Zouater, Hichem
    Ravichandran, Shoba
    Alavi, Afsaneh
    BRITISH JOURNAL OF DERMATOLOGY, 2025, 192 (04) : 629 - 640