Early aminotransferase improvement in the phase 2b NATIVE study is predictive of response pattern of liver histology as well as hepatic and cardiometabolic health markers at the end of treatment in patients with non-cirrhotic NASH

被引：0

作者：

Anstee, Quentin ^{[1
]}

Huot-Marchand, Philippe ^{[2
]}

Dzen, Lucile ^{[2
]}

Junien, Jean-Louis ^{[2
]}

Broqua, Pierre ^{[2
]}

Francque, Sven ^{[3
,5
]}

Abdelmalek, Manal ^{[4
]}

Cooreman, Michael ^{[2
]}

Harrison, Stephen

机构：

[1] Newcastle Univ, Newcastle, NSW, Australia

[2] Inventiva Res & Dev, Daix, France

[3] Antwerp Univ Hosp, Edegem, Belgium

[4] Mayo Clin, Rochester, MN USA

[5] Univ Oxford, Oxford, England

来源：

JOURNAL OF HEPATOLOGY | 2023年 / 78卷

关键词：

D O I：

暂无

中图分类号：

R57 [消化系及腹部疾病];

学科分类号：

摘要：

SAT-393

引用

页码：S651 / S651

页数：1

共 3 条

[1] THE PANPPAR AGONIST LANIFIBRANOR INDUCES BOTH RESOLUTION OF NASH AND REGRESSION OF FIBROSIS AFTER 24 WEEKS OF TREATMENT IN NON-CIRRHOTIC NASH: RESULTS OF THE NATIVE PHASE 2b TRIAL
Francque, Sven M.
Bedossa, Pierre
Ratziu, Vlad
Anstee, Quentin M.
Bugianesi, Elisabetta
Sanyal, Arun J.
Loomba, Rohit
Harrison, Stephen A.
Balabanska, Rozalina Ivanova
Mateva, Lyudmila
Lanthier, Nicolas
Alkhouri, Naim
Moreno, Christophe
Schattenberg, Jorn M.
Stefanova-Petrova, Diana
Vonghia, Luisa
Rouzier, Regine
Guillaume, Maeva
Leroy, Vincent
Romero-Gomez, Manuel
Hodge, Alexander D.
Huot-Marchand, Philippe
Sabin, Nathalie
Baudin, Martine
Abitbol, Jean-Louis
Broqua, Pierre
Junien, Jean-Louis
Abdelmalek, Manal F.
HEPATOLOGY, 2020, 72 : 9A - 11A
[2] No MK-5172 Resistance Associated Variants (RAVs) identified in a vanguard cohort of treatment-naive, genotype 1, non-cirrhotic patients enrolled in the MK-5172 phase 2B study
Barnard, Richard J.
Howe, Anita Y.
Strizki, Julie M.
Hazuda, Daria
Hwang, Peggy
Gilbert, Christopher L.
Mobashery, Niloufar
Graham, Donald
Newhard, William
McHale, Carolyn M.
HEPATOLOGY, 2012, 56 : 719A - 719A
[3] Lanifibranor therapy improves markers of lipid metabolism, insulin resistance, liver injury and fibrosis in patients with NASH and F2 and F3 fibrosis stages: a subgroup analysis of the phase 2b NATIVE study
Francque, Sven
Cooreman, Michael
Baudin, Martine
Huot-Marchand, Philippe
Dzen, Lucile
Louis, Junien Jean
Broqua, Pierre
Abdelmalek, Manal
JOURNAL OF HEPATOLOGY, 2021, 75 : S268 - S269

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