Ocimum gratissimum leaf extract and fractions alleviates trastuzumab-induced lung toxicity in Wistar rats via antioxidants and anti-apoptotic mechanisms

被引：0
|
作者：
Ajayi, Abayomi [1 ]
Olorundare, Olufunke [2 ]
Adeneye, Adejuwon [3 ]
Soyemi, Sokunle [4 ]
Mgbehoma, Alban [4 ]
Akinsola, Akinyele [2 ]
Okoye, Ikechuckwu [5 ]
Albrecht, Ralph [6 ]
Mukhtar, Hasan [7 ]
机构：
[1] Univ Ibadan, Ibadan, Nigeria
[2] Univ Ilorin, Dept Pharmacol & Therapeut, Fac Basic Clin Sci, Ilorin, Nigeria
[3] Lagos State Univ, Coll Med, Dept Pharmacol Therapeut & Toxicol, Fac Basic Clin Sci, Lagos, Nigeria
[4] Lagos State Univ, Coll Med, Dept Pathol & Forens Med, Fac Basic Clin Sci, Lagos, Nigeria
[5] Lagos State Univ, Coll Med, Dept Oral Pathol & Forens Med, Fac Dent, Lagos, Nigeria
[6] Univ Wisconsin, Dept Anim Sci, 1675 Observ Dr, Madison, WI USA
[7] Univ Wisconsin, Dept Dermatol, Madison, WI USA
来源：
BRITISH JOURNAL OF PHARMACOLOGY | 2023年 / 180卷
关键词：
D O I：
暂无
中图分类号：
R9 [药学];
学科分类号：
1007 ;
摘要：
P0456
引用
收藏
页码：866 / 867
页数：2
相关论文
共 26 条
  • [1] Safety effect of fractions from methanolic leaf extract of Ocimum gratissimum on reproduction in male wistar rats
    Njan, Anoka A.
    Olaoye, Solomon O.
    Afolabi, Saheed O.
    Ejimkonye, Benjamen C.
    Soje, Anthonia
    Olorundare, Olufunke E.
    Iwalewa, Ezekiel O.
    TOXICOLOGY REPORTS, 2019, 6 : 496 - 504
  • [2] Antidotal potential of ocimum gratissimum linn. Leaf extract and fractions against trastuzumab-mediated cardiotoxicity in rats
    Adeneye, Adejuwon
    Olorundare, Olufunke
    Ajayi, Abayomi
    Akinsola, Akinyemi
    Atolani, Olubunmi
    Soyemi, Sunday
    Mgbehoma, Alban
    BRITISH JOURNAL OF PHARMACOLOGY, 2023, 180 : 912 - 915
  • [3] Terminalia arjuna Extract Attenuates Isoproterenol-Induced Cardiac Stress in Wistar Rats via an Anti-Apoptotic Pathway
    Thangaraju M.M.
    Tamatam A.
    Bhat P.V.
    Deshetty U.M.
    Babusha S.T.
    Khanum F.
    Proceedings of the National Academy of Sciences, India Section B: Biological Sciences, 2020, 90 (5) : 1101 - 1112
  • [4] Evaluation of the anti-PCOS Potential of Ethanolic Extract of Ocimum Gratissimum (Linn.) Leaf in Letrozole-Induced Polycystic Ovarian Syndrome in Wistar Rats
    Joy, Femi-Olabisi Fehintoluwa
    Adebayo, Ishola Ahmed
    Ola, Yusuf Babalola
    Olanike, Kolawole Ikeoluwapo
    Adeola, Adesoji Precious
    CHEMISTRYSELECT, 2024, 9 (14):
  • [5] Garlic Extract Alleviates Trastuzumab-Induced Hepatotoxicity in Rats Through Its Antioxidant, Anti-Inflammatory, and Antihyperlipidemic Effects
    Mousa, Ayman M.
    Soliman, Khaled Ea
    Alhumaydhi, Fahad A.
    Almatroudi, Ahmad
    Al Rugaie, Osamah
    Allemailem, Khaled S.
    Alrumaihi, Faris
    Khan, Arif
    Rezk, Mohamad Y.
    Aljasir, Mohammad
    Alwashmi, Ameen Ss
    Alkhayl, Faris F. Aba
    Albutti, Aqel S.
    Seleem, Hanan S.
    JOURNAL OF INFLAMMATION RESEARCH, 2021, 14 : 6305 - 6316
  • [6] THE ANTI-APOPTOTIC EFFECT OF METHANOL LEAF EXTRACT OF AZADIRACHTA INDICA ON LEAD ACETATE-INDUCED APOPTOSIS IN CARDIAC AND RENAL TISSUES OF MALE WISTAR RATS
    Adeyeoluwa, Temitayo Esther
    Oyagbemi, Ademola Adetokunbo
    Adedapo, Adeolu Alex
    Omobowale, Temidayo Olutayo
    FASEB JOURNAL, 2017, 31
  • [7] Ginkgo biloba extract protects against tartrazine-induced testicular toxicity in rats: involvement of antioxidant, anti-inflammatory, and anti-apoptotic mechanisms
    Essawy, Amina
    Matar, Shreen
    Mohamed, Nema
    Abdel-Wahab, Wessam
    Abdou, Heba
    ENVIRONMENTAL SCIENCE AND POLLUTION RESEARCH, 2024, 31 (10) : 15065 - 15077
  • [8] Ginkgo biloba extract protects against tartrazine-induced testicular toxicity in rats: involvement of antioxidant, anti-inflammatory, and anti-apoptotic mechanisms
    Amina Essawy
    Shreen Matar
    Nema Mohamed
    Wessam Abdel-Wahab
    Heba Abdou
    Environmental Science and Pollution Research, 2024, 31 : 15065 - 15077
  • [9] Ceratonia siliqua pods (Carob) methanol extract alleviates doxorubicin-induced nephrotoxicity via antioxidant, anti-inflammatory and anti-apoptotic pathways in rats
    Atta, Attia H.
    Atta, Shimaa A.
    Khattab, Marwa S.
    Abd El-Aziz, Tamer H.
    Mouneir, Samar M.
    Ibrahim, Marwa A.
    Nasr, Soad M.
    Emam, Shimaa R.
    ENVIRONMENTAL SCIENCE AND POLLUTION RESEARCH, 2023, 30 (35) : 83421 - 83438
  • [10] Ceratonia siliqua pods (Carob) methanol extract alleviates doxorubicin-induced nephrotoxicity via antioxidant, anti-inflammatory and anti-apoptotic pathways in rats
    Attia H. Atta
    Shimaa A. Atta
    Marwa S. Khattab
    Tamer H. Abd El-Aziz
    Samar M. Mouneir
    Marwa A. Ibrahim
    Soad M. Nasr
    Shimaa R. Emam
    Environmental Science and Pollution Research, 2023, 30 : 83421 - 83438
123