Low-level laser efficiency in reparation of bone defects

被引:1
|
作者
Obradovic, Radmila [1 ,7 ]
Vujovic, Sanja [2 ]
Desnica, Jana [2 ]
Stevanovic, Momir [2 ]
Stanisic, Dragana [2 ]
Ognjanovic, Irena [2 ]
Mikic, Mirko [3 ]
Bijelic, Borivoj [4 ]
Subaric, Ljiljana [5 ]
Dordevic, Vladan [6 ]
机构
[1] Univ Nis, Fac Med, Nish, Serbia
[2] Univ Kragujevac, Fac Med Sci, Kragujevac, Serbia
[3] Univ Montenegro, Fac Med, Podgorica, Montenegro
[4] Univ Belgrade, Sch Dent Med, Belgrade, Serbia
[5] Univ Pristina Kosovska Mitrov, Fac Med, Kosovska Mitrovica, Serbia
[6] Univ Travnik, Fac Pharm & Hlth, Travnik, Bosnia & Herceg
[7] Univ Nis, Dept Oral Med & Periodontol, Fac Med, Bledska 2-19, Nish 18000, Serbia
关键词
bone; low-level laser treatment; osteogenesis; THERAPY; REPAIR;
D O I
10.2298/SARH220922003O
中图分类号
R5 [内科学];
学科分类号
1002 ; 100201 ;
摘要
Introduction/Objective Bone resorption is a common problem in dentistry, and bone reparation cannot be easily achieved. Several techniques of bone grafting and the use of low-level laser treatment (LLLT) as a new therapeutic optional recommended for improving bone repair were applied. The aim of the study was to investigate the influence of LLLT in bone repair of artificially made bone defects in the rat mandible using histomorphometry.Methods The research was carried out on 60 female rats. Bone defects were made in the mandible, and animals were divided into two groups, each containing 30 animals. In the study group, the implantation site was submitted to GaAlAs laser irradiation 670 nm, 5 mW, 4 minutes per day for 5 days. The control group had no postoperative treatment. The animals were sacrificed after two, six, and eight weeks post LLLT, and preparations were analysed by histomorphometry, determining bone area fraction, bone area, integral density, mean density, and density variation.Results Histomorphometric analysis revealed statistically higher values of area fraction, area, and integral density in the study group after two and six weeks. However, no beneficial laser effect was noticed after eight weeks.Conclusion Low-level lasers have a stimulating effect on reparatory mechanisms in the early regeneration stage of artificially made bone defects in the rat mandible and can be used as a useful helping method in bone treatment.
引用
收藏
页码:21 / 25
页数:5
相关论文
共 50 条
  • [1] Enhancement of bone formation in rat calvarial bone defects using low-level laser therapy
    Khadra, M
    Kasem, N
    Haanes, HR
    Ellingsen, JE
    Lyngstadaas, SP
    ORAL SURGERY ORAL MEDICINE ORAL PATHOLOGY ORAL RADIOLOGY AND ENDODONTOLOGY, 2004, 97 (06): : 693 - 700
  • [2] The influence of low-level laser therapy with alendronate irrigation on healing of bone defects in rats
    Utkan Kamil Akyol
    Sare Sipal
    Elif Demirci
    Metin Gungormus
    Lasers in Medical Science, 2015, 30 : 1141 - 1146
  • [3] The influence of low-level laser therapy with alendronate irrigation on healing of bone defects in rats
    Akyol, Utkan Kamil
    Sipal, Sare
    Demirci, Elif
    Gungormus, Metin
    LASERS IN MEDICAL SCIENCE, 2015, 30 (03) : 1141 - 1146
  • [4] Low-level laser therapy enhances the number of osteocytes in calvaria bone defects of ovariectomized rats
    Scalize, Priscilla Hakime
    de Sousa, Luiz Gustavo
    Napolitano Goncalves, Ligia Maria
    Pitol, Dimitrius Leonardo
    Palinkas, Marcelo
    Coppi, Antonio Augusto
    Righeti, Mariah Acioli
    Ricardo, Vitoria
    Bombonato-Prado, Karina Fittipaldi
    Hallak Regalo, Simone Cecilio
    Siessere, Selma
    ANIMAL MODELS AND EXPERIMENTAL MEDICINE, 2019, 2 (01) : 51 - 57
  • [5] Low-level laser therapy enhances the number of osteocytes in calvaria bone defects of ovariectomized rats
    Priscilla Hakime Scalize
    Luiz Gustavo de Sousa
    Lgia Maria Napolitano Gonalves
    Dimitrius Leonardo Pitol
    Marcelo Palinkas
    Antnio Augusto Coppi
    Mariah Acioli Righeti
    Vitria Ricardo
    Karina Fittipaldi BombonatoPrado
    Simone Ceclio Hallak Regalo
    Selma Siessere
    Animal Models and Experimental Medicine, 2019, 2 (01) : 51 - 57
  • [6] Influence of low-level laser therapy on the healing of human bone maxillofacial defects: A systematic review
    Santinoni, Carolina dos Santos
    Fernandes Oliveira, Hiskell Francine
    de Souza Batista, Victor Eduardo
    Araujo Lemos, Cleidiel Aparecido
    Verri, Fellippo Ramos
    JOURNAL OF PHOTOCHEMISTRY AND PHOTOBIOLOGY B-BIOLOGY, 2017, 169 : 83 - 89
  • [7] Low-level laser therapy enhances the number of osteocytes in calvaria bone defects of ovariectomized rats
    Priscilla Hakime Scalize
    Luiz Gustavo de Sousa
    Lígia Maria Napolitano Gon?alves
    Dimitrius Leonardo Pitol
    Marcelo Palinkas
    Ant?nio Augusto Coppi
    Mariah Acioli Righeti
    Vitória Ricardo
    Karina Fittipaldi Bombonato-Prado
    Simone Cecílio Hallak Regalo
    Selma Siessere
    Animal Models and Experimental Medicine, 2019, (01) : 51 - 57
  • [8] Effect of Low-Level Laser on the Healing of Bone Defects Filled with Autogenous Bone or Bioactive Glass: In Vivo Study
    Moreira, Guilherme Santos
    Machado Alves, Patrick Henry
    Esper, Luis Augusto
    Sbrana, Michyele Cristhiane
    Dalben, Gisele da Silva
    Neppelenbroek, Karin Hermana
    Pompeia Fraga de Almeida, Ana Lucia
    INTERNATIONAL JOURNAL OF ORAL & MAXILLOFACIAL IMPLANTS, 2018, 33 (01) : 169 - 174
  • [9] Effects of low-level laser therapy on bone healing of critical-size defects treated with bovine bone graft
    Bosco, Alvaro Francisco
    Faleiros, Paula Lazilha
    Carmona, Luana Rodrigues
    Garcia, Valdir Gouveia
    Theodoro, Leticia Helena
    de Araujo, Nathalia Januario
    Hitomi Nagata, Maria Jose
    de Almeida, Juliano Milanezi
    JOURNAL OF PHOTOCHEMISTRY AND PHOTOBIOLOGY B-BIOLOGY, 2016, 163 : 303 - 310
  • [10] Effect of Low-Level Laser on Bone Defects Treated with Bovine or Autogenous Bone Grafts: In Vivo Study in Rat Calvaria
    Cunha, Mercia J. S.
    Esper, Luis A.
    Sbrana, Michyele C.
    de Oliveira, Paula G. F. P.
    do Valle, Accacio L.
    de Almeida, Ana Lucia P. F.
    BIOMED RESEARCH INTERNATIONAL, 2014, 2014