Current progress, challenges, and future perspectives of language models for protein representation and protein design

被引：9
|
作者：
Huang, Tao [1 ]
Li, Yixue [1 ,2 ,3 ,4 ,5 ]
机构：
[1] Chinese Acad Sci, Univ Chinese Acad Sci, Shanghai Inst Nutr & Hlth, Biomed Big Data Ctr, Shanghai 200031, Peoples R China
[2] Univ Chinese Acad Sci, Hangzhou Inst Adv Study, Sch Life Sci, Key Lab Syst Hlth Sci Zhejiang Prov, Hangzhou 310024, Peoples R China
[3] Guangzhou Lab, Guangzhou 510005, Peoples R China
[4] Shanghai Jiao Tong Univ, Sch Life Sci & Biotechnol, Shanghai 200240, Peoples R China
[5] Fudan Univ, Collaborat Innovat Ctr Genet & Dev, Shanghai 200433, Peoples R China
来源：
INNOVATION | 2023年 / 4卷 / 04期
关键词：
Compendex;
D O I：
10.1016/j.xinn.2023.100446
中图分类号：
O [数理科学和化学]; P [天文学、地球科学]; Q [生物科学]; N [自然科学总论];
学科分类号：
07 ; 0710 ; 09 ;
摘要：
Proteins
引用
收藏
页数：2
相关论文
共 50 条
  • [1] Protein Quality Control in Plant Organelles: Current Progress and Future Perspectives
    Sun, Jing-Liang
    Li, Jin-Yu
    Wang, Mei-Jing
    Song, Ze-Ting
    Liu, Jian-Xiang
    [J]. MOLECULAR PLANT, 2021, 14 (01) : 95 - 114
  • [2] Computational Models of Language Evolution: Challenges and Future Perspectives
    Ferri, Fernando
    D'Ulizia, Arianna
    Grifoni, Patrizia
    [J]. JOURNAL OF UNIVERSAL COMPUTER SCIENCE, 2018, 24 (10) : 1345 - 1377
  • [3] 100 years of insulin: progress, current perspectives and future challenges
    Cantley, James
    Eizirik, Decio
    [J]. JOURNAL OF ENDOCRINOLOGY, 2022, 252 (03) : E1 - E3
  • [4] Utilizing Clostridium autoethanogenum for dietary protein in aquafeeds: Current progress in research and future perspectives
    Maulu, Sahya
    [J]. JOURNAL OF APPLIED AQUACULTURE, 2024,
  • [5] Current progress, challenges and future prospects of indazoles as protein kinase inhibitors for the treatment of cancer
    Tandon, Nitin
    Luxami, Vijay
    Kant, Divya
    Tandon, Runjhun
    Paul, Kamaldeep
    [J]. RSC ADVANCES, 2021, 11 (41) : 25228 - 25257
  • [6] Plasma protein therapies: current and future perspectives
    Farrugia, A
    Robert, P
    [J]. BEST PRACTICE & RESEARCH CLINICAL HAEMATOLOGY, 2006, 19 (01) : 243 - 258
  • [7] Targeted protein degradation: current and future challenges
    Hanzl, Alexander
    Winter, Georg E.
    [J]. CURRENT OPINION IN CHEMICAL BIOLOGY, 2020, 56 : 35 - 41
  • [8] Controllable protein design with language models
    Noelia Ferruz
    Birte Höcker
    [J]. Nature Machine Intelligence, 2022, 4 : 521 - 532
  • [9] Controllable protein design with language models
    Ferruz, Noelia
    Hoecker, Birte
    [J]. NATURE MACHINE INTELLIGENCE, 2022, 4 (06) : 521 - 532
  • [10] Energy Functions in De Novo Protein Design: Current Challenges and Future Prospects
    Li, Zhixiu
    Yang, Yuedong
    Zhan, Jian
    Dai, Liang
    Zhou, Yaoqi
    [J]. ANNUAL REVIEW OF BIOPHYSICS, VOL 42, 2013, 42 : 315 - 335
12345