Current progress, challenges, and future perspectives of language models for protein representation and protein design

被引:15
|
作者
Huang, Tao [1 ]
Li, Yixue [1 ,2 ,3 ,4 ,5 ]
机构
[1] Chinese Acad Sci, Univ Chinese Acad Sci, Shanghai Inst Nutr & Hlth, Biomed Big Data Ctr, Shanghai 200031, Peoples R China
[2] Univ Chinese Acad Sci, Hangzhou Inst Adv Study, Sch Life Sci, Key Lab Syst Hlth Sci Zhejiang Prov, Hangzhou 310024, Peoples R China
[3] Guangzhou Lab, Guangzhou 510005, Peoples R China
[4] Shanghai Jiao Tong Univ, Sch Life Sci & Biotechnol, Shanghai 200240, Peoples R China
[5] Fudan Univ, Collaborat Innovat Ctr Genet & Dev, Shanghai 200433, Peoples R China
来源
INNOVATION | 2023年 / 4卷 / 04期
关键词
Compendex;
D O I
10.1016/j.xinn.2023.100446
中图分类号
O [数理科学和化学]; P [天文学、地球科学]; Q [生物科学]; N [自然科学总论];
学科分类号
07 ; 0710 ; 09 ;
摘要
Proteins
引用
收藏
页数:2
相关论文
共 50 条
  • [1] Protein Quality Control in Plant Organelles: Current Progress and Future Perspectives
    Sun, Jing-Liang
    Li, Jin-Yu
    Wang, Mei-Jing
    Song, Ze-Ting
    Liu, Jian-Xiang
    MOLECULAR PLANT, 2021, 14 (01) : 95 - 114
  • [2] Language models for protein design
    Lee, Jin Sub
    Abdin, Osama
    Kim, Philip M.
    CURRENT OPINION IN STRUCTURAL BIOLOGY, 2025, 92
  • [3] Computational Models of Language Evolution: Challenges and Future Perspectives
    Ferri, Fernando
    D'Ulizia, Arianna
    Grifoni, Patrizia
    JOURNAL OF UNIVERSAL COMPUTER SCIENCE, 2018, 24 (10) : 1345 - 1377
  • [4] 100 years of insulin: progress, current perspectives and future challenges
    Cantley, James
    Eizirik, Decio
    JOURNAL OF ENDOCRINOLOGY, 2022, 252 (03) : E1 - E3
  • [6] Current progress, challenges and future prospects of indazoles as protein kinase inhibitors for the treatment of cancer
    Tandon, Nitin
    Luxami, Vijay
    Kant, Divya
    Tandon, Runjhun
    Paul, Kamaldeep
    RSC ADVANCES, 2021, 11 (41) : 25228 - 25257
  • [7] Plasma protein therapies: current and future perspectives
    Farrugia, A
    Robert, P
    BEST PRACTICE & RESEARCH CLINICAL HAEMATOLOGY, 2006, 19 (01) : 243 - 258
  • [8] Targeted protein degradation: current and future challenges
    Hanzl, Alexander
    Winter, Georg E.
    CURRENT OPINION IN CHEMICAL BIOLOGY, 2020, 56 : 35 - 41
  • [9] Controllable protein design with language models
    Noelia Ferruz
    Birte Höcker
    Nature Machine Intelligence, 2022, 4 : 521 - 532
  • [10] Controllable protein design with language models
    Ferruz, Noelia
    Hoecker, Birte
    NATURE MACHINE INTELLIGENCE, 2022, 4 (06) : 521 - 532