Diagnostic and progression biomarkers in cerebrospinal fluid of Alzheimer's disease patients

被引：0
|
作者：
Chatanaka, Miyo K. [1 ]
Prassas, Ioannis [2 ]
Diamandis, Eleftherios P. [3 ]
机构：
[1] Univ Toronto, Dept Lab Med & Pathobiol, Toronto, ON, Canada
[2] Univ Hlth Network, Lab Med Program, Toronto, ON, Canada
[3] Mt Sinai Hosp, Lunenfeld Tanenbaum Res Inst, Toronto, ON, Canada
来源：
BMC MEDICINE | 2024年 / 22卷 / 01期
关键词：
Alzheimer's disease; Biomarker; Non-invasive; SMOC1; Neuropentraxin; Diagnostic test; Reference range;
D O I：
10.1186/s12916-024-03270-w
中图分类号：
R5 [内科学];
学科分类号：
1002 ; 100201 ;
摘要：
In this commentary, we address a paper published by Johnson et al. by assessing the robustness of their method to discover diagnostic biomarkers in Alzheimer's disease (AD). In addition, we examine how these newly discovered and previously discovered biomarkers, can play a role in assisting patients with AD and those at risk for developing AD, with an emphasis on the translational hurdles that accompany such discoveries.
引用
下载
收藏
页数：4
相关论文
共 50 条
  • [1] Diagnostic and progression biomarkers in cerebrospinal fluid of Alzheimer’s disease patients
    Miyo K. Chatanaka
    Ioannis Prassas
    Eleftherios P. Diamandis
    BMC Medicine, 22
  • [2] Cerebrospinal fluid and blood biomarkers in the diagnostic assays of Alzheimer's disease
    Zhang, Liding
    Liang, Xiaohan
    Zhang, Zhihong
    Luo, Haiming
    JOURNAL OF INNOVATIVE OPTICAL HEALTH SCIENCES, 2022, 15 (01)
  • [3] MRI and cerebrospinal fluid biomarkers for predicting progression to Alzheimer's disease in patients with mild cognitive impairment: a diagnostic accuracy study
    Richard, Edo
    Schmand, Ben A.
    Eikelenboom, Piet
    Van Gool, Willem A.
    BMJ OPEN, 2013, 3 (06):
  • [4] Cerebrospinal fluid biomarkers of Alzheimer’s disease
    Xiaojing Sui
    Jianjun Liu
    Xifei Yang
    Neuroscience Bulletin, 2014, 30 : 233 - 242
  • [5] Cerebrospinal fluid biomarkers in Alzheimer's disease
    Hugon, Jacques
    Dumurgier, Julien
    Cognat, Emmanuel
    Paquet, Claire
    BULLETIN DE L ACADEMIE NATIONALE DE MEDECINE, 2018, 202 (1-2): : 307 - 318
  • [6] Cerebrospinal fluid biomarkers of Alzheimer's disease
    Fagan, Anne M.
    Holtzman, David M.
    BIOMARKERS IN MEDICINE, 2010, 4 (01) : 51 - 63
  • [7] Conflicting cerebrospinal fluid biomarkers and progression to dementia due to Alzheimer’s disease
    Panagiotis Alexopoulos
    Lukas Werle
    Jennifer Roesler
    Nathalie Thierjung
    Lena Sophie Gleixner
    Igor Yakushev
    Nikolaos Laskaris
    Stefan Wagenpfeil
    Philippos Gourzis
    Alexander Kurz
    Robert Perneczky
    Alzheimer's Research & Therapy, 8
  • [8] Cerebrospinal fluid biomarkers of Alzheimer's disease
    Sui, Xiaojing
    Liu, Jianjun
    Yang, Xifei
    NEUROSCIENCE BULLETIN, 2014, 30 (02) : 233 - 242
  • [9] Cerebrospinal fluid biomarkers in Alzheimer's disease
    Lee, K. H.
    JOURNAL OF NEUROCHEMISTRY, 2013, 125 : 41 - 42
  • [10] Cerebrospinal Fluid Biomarkers for Alzheimer's Disease
    Blennow, Kaj
    Zetterberg, Henrik
    JOURNAL OF ALZHEIMERS DISEASE, 2009, 18 (02) : 413 - 417
12345