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Air stable N-heterocyclic carbene silver complexes: synthesis, characterization, and antibacterial activity
被引:2
|作者:
Demir Atli, Deniz
[1
]
Aksu, Didem
[2
]
机构:
[1] Manisa Celal Bayar Univ, Fac Sci & Arts, Dept Chem, Manisa, Turkiye
[2] Ege Univ, Cent Res Testing & Anal Lab, Res & Applicat Ctr, Izmir, Turkiye
关键词:
Benzimidazolium salt;
N-heterocyclic carbene;
silver complex;
antibacterial studies;
CARBENE-SILVER(I);
D O I:
10.1080/00958972.2023.2251077
中图分类号:
O61 [无机化学];
学科分类号:
070301 ;
081704 ;
摘要:
A new benzimidazolium salt containing a 2,5-dimethylbenzyl substituent and six N-heterocyclic carbene (NHC) silver complexes were prepared. The complexes were characterized by NMR, FTIR, and LC-MS spectroscopic methods and elemental analyses. They are stable in solution for a week. The antibacterial properties of the Ag(I) complexes against two Gram-positive and two Gram-negative bacteria were investigated. Inhibition zone and minimum inhibitory concentration (MIC) data establish that these NHC-Ag(I) complexes possess antibacterial activities; 2b showed the highest antibacterial activity overall against Gram-positive and Gram-negative bacteria.
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页码:1497 / 1506
页数:10
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