Evaluation of the efficacy of probiotics as treatment in irritable bowel syndrome

被引:1
|
作者
Ruiz-Sanchez, Cristina [1 ]
Escudero-Lopez, Blanca [1 ]
Fernandez-Pachon, Maria-Soledad [1 ]
机构
[1] Univ Pablo Olavide, Dept Biol Mol & Ingn Bioquim, Area Nutr Bromatol, Seville, Spain
来源
ENDOCRINOLOGIA DIABETES Y NUTRICION | 2024年 / 71卷 / 01期
关键词
Microbiota; Irritable bowel syndrome; Probiotics; RANDOMIZED CLINICAL-TRIAL; FUNCTIONAL GASTROINTESTINAL DISORDERS; DOUBLE-BLIND; LACTOBACILLUS-ACIDOPHILUS; PLACEBO; SYMPTOMS; BIFIDOBACTERIUM; SUPPLEMENTATION; MICROBIOTA; MIXTURE;
D O I
10.1016/j.endien.2024.01.003
中图分类号
R5 [内科学];
学科分类号
1002 ; 100201 ;
摘要
Irritable bowel syndrome (IBS) is a gastrointestinal functional disorder mainly characterised by abdominal pain, bloating and altered bowel habits. Dysbiosis might seem to be involved in the pathogenesis of the disease. Probiotics represent a potential treatment, since these could favour the functional microbiota and improve symptoms. The aim was to review the effectiveness of the use of probiotics in IBS symptomatology, analysing the influence of duration and dose. 18 articles were included. At the individual level, Lactobacillus, Bifidobacterium and Bacillus could be useful in the treatment of symptoms. Bifidobacterium bifidum reported the best results (1 x 109 CFU/day for 4 weeks). The most effective combination was 2 Lactobacillus strains, one of Bifidobacterium and one of Streptococcus (4 x 109 CFU/day for 4 weeks). Future clinical trials should confirm these results and analyse the difference between individual and combined treatments. (c) 2023 The Author(s). Published by Elsevier Espan similar to a, S.L.U. on behalf of SEEN and SED. This is an open access article under the CC BY-NC-ND license (http://creativecommons.org/licenses/ by-nc-nd/4.0/).
引用
收藏
页码:19 / 30
页数:12
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