Irritable bowel syndrome (IBS) is a gastrointestinal functional disorder mainly characterised by abdominal pain, bloating and altered bowel habits. Dysbiosis might seem to be involved in the pathogenesis of the disease. Probiotics represent a potential treatment, since these could favour the functional microbiota and improve symptoms. The aim was to review the effectiveness of the use of probiotics in IBS symptomatology, analysing the influence of duration and dose. 18 articles were included. At the individual level, Lactobacillus, Bifidobacterium and Bacillus could be useful in the treatment of symptoms. Bifidobacterium bifidum reported the best results (1 x 109 CFU/day for 4 weeks). The most effective combination was 2 Lactobacillus strains, one of Bifidobacterium and one of Streptococcus (4 x 109 CFU/day for 4 weeks). Future clinical trials should confirm these results and analyse the difference between individual and combined treatments. (c) 2023 The Author(s). Published by Elsevier Espan similar to a, S.L.U. on behalf of SEEN and SED. This is an open access article under the CC BY-NC-ND license (http://creativecommons.org/licenses/ by-nc-nd/4.0/).
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McMaster Univ, Med Ctr, Dept Med, Div Gastroenterol, Hamilton, ON L8N 3Z5, CanadaMcMaster Univ, Med Ctr, Dept Med, Div Gastroenterol, Hamilton, ON L8N 3Z5, Canada
Moayyedi, P.
Ford, A. C.
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机构:McMaster Univ, Med Ctr, Dept Med, Div Gastroenterol, Hamilton, ON L8N 3Z5, Canada
Ford, A. C.
Talley, N. J.
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Mayo Clin, Jacksonville, FL 32224 USAMcMaster Univ, Med Ctr, Dept Med, Div Gastroenterol, Hamilton, ON L8N 3Z5, Canada
Talley, N. J.
Cremonini, F.
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Mayo Clin, Rochester, MN USAMcMaster Univ, Med Ctr, Dept Med, Div Gastroenterol, Hamilton, ON L8N 3Z5, Canada
Cremonini, F.
Foxx-Orenstein, A. E.
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Mayo Clin, Rochester, MN USAMcMaster Univ, Med Ctr, Dept Med, Div Gastroenterol, Hamilton, ON L8N 3Z5, Canada
Foxx-Orenstein, A. E.
Brandt, L. J.
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Montefiore Med Ctr, Bronx, NY 10467 USAMcMaster Univ, Med Ctr, Dept Med, Div Gastroenterol, Hamilton, ON L8N 3Z5, Canada
Brandt, L. J.
Quigley, E. M. M.
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Natl Univ Ireland Univ Coll Cork, Dept Med, Alimentary Pharmabiot Ctr, Cork, IrelandMcMaster Univ, Med Ctr, Dept Med, Div Gastroenterol, Hamilton, ON L8N 3Z5, Canada
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Wayne State Univ, Eugene Applkebaum Coll Pharm & Hlth Sci, Detroit, MI 48202 USASt Johns Hosp, Detroit, MI 48236 USA
Wilhelm, Sheila M.
Brubaker, Christine M.
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Wayne State Univ, Eugene Applkebaum Coll Pharm & Hlth Sci, Detroit, MI 48202 USASt Johns Hosp, Detroit, MI 48236 USA
Brubaker, Christine M.
Varcak, Elizabeth A.
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Wayne State Univ, Eugene Applkebaum Coll Pharm & Hlth Sci, Detroit, MI 48202 USASt Johns Hosp, Detroit, MI 48236 USA
Varcak, Elizabeth A.
Kale-Pradhan, Pramodini B.
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St Johns Hosp, Detroit, MI 48236 USA
Wayne State Univ, Eugene Applkebaum Coll Pharm & Hlth Sci, Detroit, MI 48202 USASt Johns Hosp, Detroit, MI 48236 USA
机构:
Department of Cadre Ward V, First Affiliated Hospital, China Medical UniversityDepartment of Cadre Ward V, First Affiliated Hospital, China Medical University
Cong Dai
Chang-Qing Zheng
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Department of Gastroenterology, Second Affiliated Hospital, China Medical UniversityDepartment of Cadre Ward V, First Affiliated Hospital, China Medical University
Chang-Qing Zheng
Min Jiang
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Department of Gastroenterology, First Affiliated Hospital, China Medical UniversityDepartment of Cadre Ward V, First Affiliated Hospital, China Medical University
Min Jiang
Xiao-Yu Ma
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Department of Cadre Ward V, First Affiliated Hospital, China Medical UniversityDepartment of Cadre Ward V, First Affiliated Hospital, China Medical University
Xiao-Yu Ma
Li-Juan Jiang
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Department of Cadre Ward V, First Affiliated Hospital, China Medical UniversityDepartment of Cadre Ward V, First Affiliated Hospital, China Medical University
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Minist Hlth & Med Educ, Food & Drug Org, Drug Selecting Committee, Tehran, IranMinist Hlth & Med Educ, Food & Drug Org, Drug Selecting Committee, Tehran, Iran
Nikfar, Shekoufeh
Rahimi, Roja
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Univ Tehran Med Sci, Fac Pharm, Tehran, Iran
Univ Tehran Med Sci, Pharmaceut Sci Res Ctr, Tehran, IranMinist Hlth & Med Educ, Food & Drug Org, Drug Selecting Committee, Tehran, Iran
Rahimi, Roja
Rahimi, Fatemeh
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Univ Tehran Med Sci, Fac Pharm, Tehran, Iran
Univ Tehran Med Sci, Pharmaceut Sci Res Ctr, Tehran, IranMinist Hlth & Med Educ, Food & Drug Org, Drug Selecting Committee, Tehran, Iran
Rahimi, Fatemeh
Derakhshani, Saeed
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Baharan Colorectal Surg Ctr, Tehran, IranMinist Hlth & Med Educ, Food & Drug Org, Drug Selecting Committee, Tehran, Iran
Derakhshani, Saeed
Abdollahi, Mohammad
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Univ Tehran Med Sci, Fac Pharm, Tehran, Iran
Univ Tehran Med Sci, Pharmaceut Sci Res Ctr, Tehran, IranMinist Hlth & Med Educ, Food & Drug Org, Drug Selecting Committee, Tehran, Iran