Radiological and Functional Pulmonary Evolution in Post-COVID-19 Patients: An Observational Study

被引:1
|
作者
Cavallari Strozze Catharin, Virginia Maria [1 ]
Zutin, Tereza Lais Menegucci [1 ,2 ]
Guiguer, Elen Landgraf [1 ,2 ,3 ]
Cressoni Araujo, Adriano [1 ,2 ]
Fornari Laurindo, Lucas [1 ,4 ]
Chagas, Eduardo F. Baisi [1 ,2 ]
Gasparotti Zorzetto, Cassia Fernanda [1 ]
Bueno, Patricia C. dos Santos [1 ,5 ]
dos Santos Bueno, Manoela [6 ]
Cervelim Nunes, Yandra [3 ]
Cavallari Strozze Catharin, Vitor [1 ]
Gonzaga, Heron Fernando [7 ]
Barbalho, Sandra Maria [1 ,2 ,3 ]
机构
[1] Univ Marilia UNIMAR, Sch Med, Dept Biochem & Pharmacol, Ave Hygino Muzzy Filho, 1001, BR-17525902 Sao Paulo, Brazil
[2] Univ Marilia UNIMAR, Postgrad Program Struct & Funct Interact Rehabil, Ave Hygino Muzzy Filho, 1001, BR-17525902 Sao Paulo, Brazil
[3] Sch Food & Technol Marilia FATEC, Dept Biochem & Nutr, Ave Castro Alves, 62, BR-17500000 Sao Paulo, Brazil
[4] Fac Med Marilia FAMEMA, Sch Med, Dept Biochem & Pharmacol, Ave Monte Carmelo, 800, BR-17519030 Sao Paulo, Brazil
[5] Univ Marilia UNIMAR, Sch Vet Med, Dept Anim Sci, Ave Hygino Muzzy Filho, 1001, BR-17525902 Sao Paulo, Brazil
[6] UNIMED Marilia R Bororos, 225225 Sen Salgado Filho, BR-17502270 Sao Paulo, Brazil
[7] Fed Univ Sao Paulo UNIFESP, Escola Paulista Med, Dept Dermatol, Rua Otonis, 861, BR-04025002 Sao Paulo, SP, Brazil
关键词
COVID-19; post-COVID-19; pulmonary manifestations; spirometry; chest tomography; CORONAVIRUS DISEASE 2019; CLINICAL CHARACTERISTICS; COVID-19;
D O I
10.3390/diseases11030113
中图分类号
R-3 [医学研究方法]; R3 [基础医学];
学科分类号
1001 ;
摘要
COVID-19 has generated a scenario for global health with multiple systemic impairments. This retrospective study evaluated the clinical, radiological, and pulmonary functional evolution in 302 post-COVID-19 patients. Regarding post-COVID-19 pulmonary symptoms, dry cough, dyspnea, and chest pain were the most frequent. Of the associated comorbidities, asthma was more frequent (23.5%). Chest tomography (CT) initially showed a mean pulmonary involvement of 69.7%, and evaluation in the subsequent months showed improvement in the evolutionary image. With less than six months post-pathology, there was a commitment of 37.7% from six to twelve months it was 20%, and after 12 months it was 9.9%. As for most of the sample, 50.3% of the patients presented CT normalization less than six months after infection, 23% were normalized between six and twelve months, and 5.2% presented with normalized images after twelve months, with one remaining. A percentage of 17.3% maintained post-COVID-19 pulmonary residual sequelae. Regarding spirometry, less than six months after pathology, 59.3% of the patients presented regular exam results, 12.3% had their function normalized within six to twelve months, and 6.3% had normal exam results twelve months after their post-pathology evaluation. Only 3.6% of the patients still showed some alteration during this period.
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页数:11
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